APRISO
Generic: mesalamine
- Manufacturer
- Salix
- NDC
- 65649-103
- RxCUI
- 825130
- Route
- ORAL
- ICD-10 indication
- I10
Affordability Check
How much will you actually pay for APRISO?
In 30 seconds, see every legitimate way to afford APRISO — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About APRISO
What is this medication? Apriso is a prescription medication used to maintain the remission of ulcerative colitis in adult patients. Ulcerative colitis is a chronic inflammatory bowel disease that affects the lining of the large intestine and rectum, often causing symptoms such as abdominal pain and frequent diarrhea. As an extended-release form of the active ingredient mesalamine, this drug is specifically designed to target the colon and reduce the inflammation associated with the condition.
This medication belongs to a class of drugs called aminosalicylates, which work by suppressing the production of certain chemicals that cause inflammation in the gut. By keeping the inflammation under control, Apriso helps prevent future flare-ups and keeps the disease in a state of remission. It is typically taken once per day and is intended for long-term use even when symptoms are not present to ensure the digestive system remains stable.
Copay & patient assistance
- Patient Copay Amount: $0 (Medication is provided for free to eligible patients)
- Maximum Annual Benefit Limit: Not Publicly Available (Patients can receive medication for up to 1 year and may reapply annually)
- Core Eligibility Restrictions: Patients must have limited or no insurance coverage; specifically includes Medicaid patients whose plans stopped covering Bausch Health medications as of October 1, 2025; must demonstrate financial need and have a valid prescription.
- RxBIN, PCN, and Group numbers: Not Publicly Available (Medication is shipped directly to the patient's home rather than processed via a retail pharmacy card)
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for mesalamine.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup APRISO →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for mesalamine →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How APRISO appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
0%
2 of 5,499 plans
Most common tier
Tier 1
On 100% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 1 | 100% |
Step therapy: 0% of formularies
Quantity limits: 100% of formularies
Coverage breadth: 1 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.