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BACTERIOSTATIC WATER

Generic: Bacteriostatic Water

Verified·Apr 23, 2026
Manufacturer
Hospira
NDC
51662-1473
Route
INTRAMUSCULAR
ICD-10 indication
Z76.89

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About BACTERIOSTATIC WATER

What is this medication? Bacteriostatic Water for Injection is a sterile, non-pyrogenic preparation of distilled water that contains 0.9 percent benzyl alcohol added as a preservative. This solution is specifically designed to serve as a diluent or solvent for medications that must be administered through injection, such as those delivered intravenously, intramuscularly, or subcutaneously. It allows for the safe reconstitution of powdered drugs or the dilution of concentrated liquid medications into a form that can be easily injected into the body.

The presence of benzyl alcohol as a bacteriostatic agent inhibits the growth of most potentially contaminating bacteria, allowing a single vial to be accessed multiple times for up to 28 days. Despite its versatility for multi-dose use, this medication must never be used in newborns or infants, as the preservative can lead to serious toxicity in young children. Additionally, it is intended only for use as a vehicle for other drugs and should not be injected directly into a patient without being mixed with a compatible medication first.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for BACTERIOSTATIC WATER. Official source: DailyMed (NLM) · Label effective Jan 8, 2025

Indications and usage
INDICATIONS & USAGE This parenteral preparation is indicated only for diluting or dissolving drugs for intravenous, intramuscular or subcutaneous injection, according to instructions of the manufacturer of the drug to be administered.
Dosage and administration
DOSAGE & ADMINISTRATION The volume of the preparation to be used for diluting or dissolving any drug for injection is dependent on the vehicle concentration, dose and route of administration as recommended by the manufacturer. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS .
Contraindications
CONTRAINDICATIONS Due to the potential toxicity of benzyl alcohol in neonates, solutions containing benzyl alcohol must not be used in this patient population. Parenteral preparations with benzyl alcohol should not be used for fluid replacement. Parenteral preparations containing benzyl alcohol should not be used in epidural or spinal anesthesia procedures. Bacteriostatic Water for Injection, USP must be made approximately isotonic prior to use.
Warnings
WARNINGS Benzyl alcohol, a preservative in Bacteriostatic Water for Injection, USP has been associated with toxicity in neonates. Data are unavailable on the toxicity of other preservatives in this age group. Where water is required for preparing or diluting medications for use in neonates, only preservative-free Sterile Water for Injection should be used. Intravenous administration of Bacteriostatic Water for Injection without a solute may result in hemolysis.
Adverse reactions
ADVERSE REACTIONS Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate countermeasures, and if possible, retrieve and save the remainder of the unused vehicle for examination. Although adverse reactions to intravenous, intramuscular or subcutaneous injection of 0.9% benzyl alcohol are not known to occur in man, experimental studies of small volume parenteral preparations containing 0.9% benzyl alcohol in several species of animals have indicated that an estimated intravenous dose up to 30 mL may be safely given to an adult without toxic effects. Administration of an estimated 9 mL to a 6 kg infant or neonate is potentially capable of producing blood pressure changes.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.