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BETAMETHASONE DIPROPIONATE

Generic: Betamethasone dipropionate

Verified·Apr 23, 2026
Manufacturer
Organon
NDC
51672-1274
RxCUI
238920
Route
TOPICAL
ICD-10 indication
L30.9

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About BETAMETHASONE DIPROPIONATE

What is this medication? Betamethasone dipropionate is a potent corticosteroid medication primarily used to treat a wide range of inflammatory skin conditions. It is frequently prescribed for patients suffering from eczema, psoriasis, and various types of dermatitis. By suppressing the immune response in the local area of application, this medication effectively reduces the redness, swelling, and intense itching that often accompany these chronic or acute skin disorders.

The medication is available in several topical forms, including creams, ointments, lotions, and gels, allowing it to be used on different parts of the body. Because it is a high-potency steroid, it is typically used for short periods to manage flare-ups rather than for long-term maintenance. Patients are usually advised to apply a thin layer to the affected area once or twice daily, following specific medical guidance to minimize the risk of side effects such as skin thinning or irritation.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for BETAMETHASONE DIPROPIONATE. Official source: DailyMed (NLM) · Label effective Jul 2, 2025

Indications and usage
INDICATIONS AND USAGE Betamethasone dipropionate cream is a medium-potency corticosteroid indicated for relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses in patients 13 years and older.
Dosage and administration
DOSAGE AND ADMINISTRATION Apply a thin film of betamethasone dipropionate cream USP, 0.05% to the affected skin areas once daily. In some cases, twice-daily dosage may be necessary. Betamethasone dipropionate cream USP, 0.05% should not be used with occlusive dressings.
Contraindications
CONTRAINDICATIONS Betamethasone dipropionate cream is contraindicated in patients who are hypersensitive to betamethasone dipropionate, to other corticosteroids, or to any ingredient in this preparation.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently when betamethasone dipropionate cream USP, 0.05% is used as recommended in the DOSAGE AND ADMINISTRATION section. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria. Adverse reactions reported to be possibly or probably related to treatment with betamethasone dipropionate cream during a pedatric clinical study include signs of skin atrophy (brusing, shininess). Skin atrophy occurred in 3 of 63 (5%) patients, a 3-year old, a 5-year old, and a 7-year old. Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Use in pregnancy
Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Betamethasone dipropionate has been shown to be teratogenic in rabbits when given by the intramuscular route at doses of 0.05 mg/kg. This dose is approximately 0.03 fold the estimated maximum human dose based on a mg/m 2 comparison. The abnormalities observed included umbilical hernias, cephalocele and cleft palates. Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How BETAMETHASONE DIPROPIONATE appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

71%

3,926 of 5,509 plans

Most common tier

Tier 3

On 34% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)67
20%
Tier 2 (generic)105
32%
Tier 3 (preferred brand)112
34%
Tier 4 (non-preferred brand)44
13%

Step therapy: 0% of formularies

Quantity limits: 50% of formularies

Coverage breadth: 328 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.