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Betamethasone Dipropionate USP, 0.05%

Generic: Betamethasone Dipropionate USP, 0.05%

Verified·Apr 23, 2026
Manufacturer
Organon
NDC
52817-824
RxCUI
197405
Route
TOPICAL
ICD-10 indication
L40.0

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About Betamethasone Dipropionate USP, 0.05%

What is this medication? Betamethasone dipropionate USP, 0.05% is a high-potency topical corticosteroid used to treat a variety of inflammatory skin conditions. It is specifically formulated to address symptoms such as redness, swelling, and intense itching that occur during skin flare-ups. This medication is available in several forms, including creams, ointments, and lotions, and is typically applied directly to the affected skin area as directed by a healthcare professional. The medication works by suppressing the immune system response in the local skin tissue, which reduces the release of chemicals that cause inflammation. It is commonly prescribed for chronic or acute conditions such as plaque psoriasis, atopic dermatitis, and allergic contact dermatitis. Because it is a potent steroid, it is generally used for short durations to manage symptoms effectively while minimizing the risk of side effects like skin thinning.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Betamethasone Dipropionate USP, 0.05%. Official source: DailyMed (NLM) · Label effective Jan 18, 2026

Indications and usage
INDICATIONS AND USAGE Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION Apply a thin film of betamethasone dipropionate ointment to the affected skin areas once daily. In some cases, twice daily dosage may be necessary. If an infection develops, appropriate antimicrobial therapy should be instituted. Betamethasone dipropionate ointment should not be used with occlusive dressings.
Contraindications
CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently when betamethasone dipropionate ointment is used as recommended in the DOSAGE AND ADMINISTRATION section. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infections, skin atrophy, striae and miliaria. Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia and glucosuria in some patients.
Use in pregnancy
PREGNANCY Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Betamethasone Dipropionate USP, 0.05% appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

71%

3,921 of 5,509 plans

Most common tier

Tier 4

On 39% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)65
20%
Tier 2 (generic)95
29%
Tier 3 (preferred brand)40
12%
Tier 4 (non-preferred brand)126
39%

Step therapy: 0% of formularies

Quantity limits: 53% of formularies

Coverage breadth: 326 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.