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BSS PLUS

Generic: balanced salt solution enriched with bicarbonate, dextrose, and glutathione

Verified·Apr 23, 2026
Manufacturer
Alcon
NDC
0065-0800
ICD-10 indication
H26.9

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About BSS PLUS

What is this medication? BSS PLUS is a sterile intraocular irrigating solution used primarily during surgical procedures involving the eye. It is an enriched version of standard balanced salt solution, containing essential electrolytes and additives like glutathione, dextrose, and bicarbonate. These components are designed to mimic the natural aqueous humor of the eye, providing necessary nutrients and maintaining the physiological balance of intraocular tissues during prolonged operations.

Surgeons typically use this medication during complex procedures such as vitrectomies or cataract removals to irrigate the anterior and posterior chambers. By keeping the eye tissues hydrated and providing metabolic support, BSS PLUS helps protect the delicate corneal endothelial cells from damage. This support is crucial for maintaining corneal clarity and ensuring better recovery outcomes for patients undergoing invasive ophthalmic surgery.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for BSS PLUS. Official source: DailyMed (NLM) · Label effective Jan 25, 2024

Indications and usage
INDICATIONS AND USAGE: BSS PLUS solution is indicated for use as an intraocular irrigating solution during intraocular surgical procedures involving perfusion of the eye.
Dosage and administration
DOSAGE AND ADMINISTRATION The solution should be used according to the standard technique employed by the operating surgeon. Use an administration set with an air-inlet in the plastic spike since the bag does not contain a separate airway tube. Follow the directions for the particular administration set to be used. Insert the spike aseptically into the bag through the center target area of the rubber stopper. Allow the fluid to flow to remove air from the tubing before intraocular irrigation begins.
Contraindications
CONTRAINDICATIONS There are no specific contraindications to the use of BSS PLUS solution; however, contraindications for the surgical procedure during which BSS PLUS solution is to be used should be strictly adhered to.
Warnings
WARNINGS For IRRIGATION during ophthalmic surgery only. Not for injection or intravenous infusion. Do not use unless product is clear, seal is intact and container is undamaged. Do not use if product is discolored or contains a precipitate.
Adverse reactions
ADVERSE REACTIONS Postoperative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported. Their relationship to the use of BSS PLUS solution has not been established.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.