How much does CILOXAN cost?

Pricing for CILOXAN varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does CILOXAN need prior authorization?

CILOXAN appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for CILOXAN?

Yes — the manufacturer copay card link is available on this page. A patient assistance program is also available for qualifying patients. Eligibility typically depends on insurance type and income. Click the CTA buttons above to apply directly through the manufacturer's portal.

What is CILOXAN used to treat?

CILOXAN (generic: ciprofloxacin hydrochloride) is indicated for Conjunctivitis. Click any condition name on this page for more detail.

Does CILOXAN have a generic version?

The generic name for CILOXAN is ciprofloxacin hydrochloride. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

CILOXAN

Generic: ciprofloxacin hydrochloride

Verified·Apr 23, 2026

Manufacturer: Alcon
NDC: 66758-071
RxCUI: 213307
Route: OPHTHALMIC
ICD-10 indication: H10.30

Affordability Check

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About CILOXAN

What is this medication?

Ciloxan is a prescription antibiotic medication that contains the active ingredient ciprofloxacin. It belongs to a class of drugs known as fluoroquinolones and is specifically formulated for use in the eyes. This medication is primarily prescribed to treat bacterial infections such as bacterial conjunctivitis, commonly known as pink eye, and corneal ulcers. It is available in both liquid drop and ointment forms to target the affected area directly and provide relief from symptoms like redness, discharge, and irritation.

The medication works by interfering with the enzymes that bacteria need to repair and replicate their DNA, effectively killing the bacteria or preventing them from multiplying. Because it is an antibiotic, it is only effective against bacterial infections and will not work for viral or fungal issues. To ensure the infection is fully resolved and to help prevent the bacteria from becoming resistant to the drug, it is essential for patients to use the medication for the entire duration prescribed by their doctor, even if symptoms improve quickly.

Copay & patient assistance

Patient Copay Amount: Pay as little as $30 (EYSUVIS); First Fill Free (TRYPTYR); $79 for patients without Medicare Part D coverage (Rocklatan, Rhopressa, and Simbrinza); $60 for patients with Medicare Part D (Inveltys); $0 for eligible patients via Alcon Cares Patient Assistance.
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Varies by program; Copay assistance is for patients with private insurance; BlinkRx support is available for Commercial and Medicare patients; Patient Assistance (Alcon Cares) requires US residency, limited or no private or public prescription coverage, and meeting specific household income requirements.
RxBIN, PCN, and Group numbers: Not Publicly Available

Copay card →Patient Assistance Program →

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for ciprofloxacin hydrochloride.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup CILOXAN →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for ciprofloxacin hydrochloride →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for CILOXAN. Official source: DailyMed (NLM) · Label effective Jul 30, 2024

Indications and usage

INDICATIONS AND USAGE: CILOXAN ® (ciprofloxacin ophthalmic ointment) 0.3% is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the microorganisms listed below: Gram-Positive: Staphylococcus aureus Staphylococcus epidermidis Streptococcus pneumoniae Streptococcus Viridans Group Gram-Negative: Haemophilus influenzae

Dosage and administration

DOSAGE AND ADMINISTRATION: Apply a ½ inch ribbon into the conjunctival sac three times a day on the first two days, then apply a ½ inch ribbon two times a day for the next five days.

Contraindications

CONTRAINDICATIONS: A history of hypersensitivity to ciprofloxacin or any other component of the medication is a contraindication to its use. A history of hypersensitivity to other quinolones may also contraindicate the use of ciprofloxacin.

Warnings

WARNINGS: FOR EYE USE ONLY NOT FOR INJECTION INTO THE EYE Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported in patients receiving systemic quinolone therapy. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal or facial edema, dyspnea, urticaria, and itching. Only a few patients had a history of hypersensitivity reactions. Serious anaphylactic reactions require immediate emergency treatment with epinephrine and other resuscitation measures, including oxygen, intravenous fluids, intravenous antihistamines, corticosteroids, pressor amines, and airway management, as clinically indicated.

Drug interactions

Drug Interactions: Specific drug interaction studies have not been conducted with ophthalmic ciprofloxacin. However, the systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, enhance the effects of the oral anticoagulant, warfarin, and its derivatives, and has been associated with transient elevations in serum creatinine in patients receiving cyclosporine concomitantly.

Adverse reactions

ADVERSE REACTIONS: The following adverse reactions (incidences) were reported in 2% of the patients in clinical studies for CILOXAN ® (ciprofloxacin ophthalmic ointment) 0.3%: discomfort and keratopathy. Other reactions associated with ciprofloxacin therapy occurring in less than 1% of patients included allergic reactions, blurred vision, corneal staining, decreased visual acuity, dry eye, edema, epitheliopathy, eye pain, foreign body sensation, hyperemia, irritation, keratoconjunctivitis, lid erythema, lid margin hyperemia, photophobia, pruritus, and tearing. Systemic adverse reactions related to ciprofloxacin therapy occurred at an incidence below 1% and included dermatitis, nausea and taste perversion.

Use in pregnancy

Pregnancy: Reproduction studies have been performed in rats and mice at doses up to six times the usual daily human oral dose and have revealed no evidence of impaired fertility or harm to the fetus due to ciprofloxacin. In rabbits, as with most antimicrobial agents, ciprofloxacin (30 and 100 mg/kg orally) produced gastrointestinal disturbances resulting in maternal weight loss and an increased incidence of abortion. No teratogenicity was observed at either dose. After intravenous administration, at doses up to 20 mg/kg, no maternal toxicity was produced and no embryotoxicity or teratogenicity was observed. There are no adequate and well controlled studies in pregnant women. CILOXAN ® (ciprofloxacin ophthalmic ointment) 0.3% should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Conjunctivitis

Medicare Part D coverage

How CILOXAN appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

28%

1,560 of 5,509 plans

Most common tier

Tier 3

On 66% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	13	16%
Tier 2 (generic)	2	3%
Tier 3 (preferred brand)	53	66%
Tier 4 (non-preferred brand)	12	15%

Step therapy: 0% of formularies

Quantity limits: 9% of formularies

Coverage breadth: 80 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.