How much does Clobetasol Propionate cost?

Pricing for Clobetasol Propionate varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Clobetasol Propionate need prior authorization?

Clobetasol Propionate appears on 3 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Clobetasol Propionate?

Yes — the manufacturer copay card link is available on this page. A patient assistance program is also available for qualifying patients. Eligibility typically depends on insurance type and income. Click the CTA buttons above to apply directly through the manufacturer's portal.

What is Clobetasol Propionate used to treat?

Clobetasol Propionate (generic: clobetasol propionate) is indicated for Psoriasis, Plaque Psoriasis. Click any condition name on this page for more detail.

Clobetasol Propionate

Generic: clobetasol propionate

Verified·Apr 23, 2026

Manufacturer: GlaxoSmithKline
NDC: 46708-465
RxCUI: 861487
Route: TOPICAL
ICD-10 indication: L40.0

Affordability Check

How much will you actually pay for Clobetasol Propionate?

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About Clobetasol Propionate

What is this medication?

Clobetasol propionate is a highly potent topical corticosteroid used to treat various inflammatory skin disorders. It is most commonly prescribed for patients dealing with severe cases of psoriasis, eczema, and recalcitrant dermatitis. The medication works by decreasing the activity of chemicals in the body that cause inflammation, which effectively reduces redness, swelling, and intense itching associated with these conditions.

This prescription treatment is available in several forms including creams, ointments, gels, and foams to provide relief for different skin textures and body areas. Due to its extreme potency, it is generally recommended for short-term use only, typically not exceeding two weeks at a time. Using the medication as directed helps prevent skin thinning and other potential side effects, and it should generally be avoided on sensitive areas like the face, groin, or armpits unless otherwise instructed by a physician.

Copay & patient assistance

Patient Copay Amount: Free (for patients who qualify for the Patient Assistance Program)
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Patients must have a demonstrated financial need and be prescribed a medication included in the Viatris Patient Assistance Program (U.S.)
RxBIN, PCN, and Group numbers: Not Publicly Available

Copay card →Patient Assistance Program →

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for clobetasol propionate.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Clobetasol Propionate →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for clobetasol propionate →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Clobetasol Propionate. Official source: DailyMed (NLM) · Label effective Feb 12, 2025

Indications and usage

INDICATIONS AND USAGE Clobetasol Propionate Ointment USP, 0.05% is super-high potency corticosteroid formulations indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in pediatric patients under 12 years of age is not recommended. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.

Dosage and administration

DOSAGE AND ADMINISTRATION Apply a thin layer of clobetasol propionate ointment to the affected skin areas twice daily and rub in gently and completely. (See INDICATIONS AND USAGE ). Clobetasol propionate ointment is super-high potency topical corticosteroids; therefore, treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Clobetasol propionate ointment should not be used with occlusive dressings. Geriatric Use: In studies where geriatric patients (65 years of age or older, see PRECAUTIONS) have been treated with clobetasol propionate ointment, safety did not differ from that in younger patients; therefore, no dosage adjustment is recommended.

Contraindications

CONTRAINDICATIONS Clobetasol propionate ointment is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.

Adverse reactions

ADVERSE REACTIONS In controlled clinical trials, the most frequent adverse events reported for clobetasol propionate ointment were burning sensation, irritation, and itching in 0.5% of treated patients. Less frequent adverse reactions were stinging, cracking, erythema, folliculitis, numbness of fingers, skin atrophy, and telangiectasia. Cushing's syndrome has been reported in infants and adults as a result of prolonged use of topical clobetasol propionate formulations. The following additional local adverse reactions have been reported with topical corticosteroids, and they may occur more frequently with the use of occlusive dressings and higher potency corticosteroids. These reactions are listed in an approximately decreasing order of occurrence: dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, irritation, striae, and miliaria. To report SUSPECTED ADVERSE REACTIONS, contact FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Clobetasol Propionate appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

65%

3,592 of 5,509 plans

Most common tier

Tier 4

On 46% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	60	23%
Tier 2 (generic)	74	28%
Tier 3 (preferred brand)	10	4%
Tier 4 (non-preferred brand)	121	46%

Step therapy: 0% of formularies

Quantity limits: 60% of formularies

Coverage breadth: 265 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

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Medicare Part D

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Medicare Part D

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Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.