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erythromycin topical solution 2%

Verified·Apr 23, 2026
Manufacturer
Bausch Health
NDC
71656-030
ICD-10 indication
L70.0

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About erythromycin topical solution 2%

What is this medication?

Erythromycin topical solution 2 percent is a prescription antibiotic medication used primarily for the treatment of common acne, also known as acne vulgaris. This solution works by stopping the growth of bacteria that contribute to acne outbreaks and by reducing the overall inflammation associated with skin lesions. It is specifically formulated to be applied directly to the skin surface where it targets the bacteria deep within the pores and oil glands.

In addition to its antibacterial properties, the medication helps to decrease the amount of free fatty acids on the skin surface, which can further reduce irritation and prevent new pimples from forming. Healthcare providers typically prescribe this liquid solution for use once or twice daily on clean, dry skin in the affected areas. While it is highly effective at controlling bacterial growth, it is often used as part of a comprehensive skin care regimen to maintain clearer skin over time.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for erythromycin topical solution 2%. Official source: DailyMed (NLM) · Label effective Aug 14, 2024

Indications and usage
INDICATIONS AND USAGE Erythromycin topical solution, 2% is indicated for the topical treatment of acne vulgaris.
Dosage and administration
DOSAGE AND ADMINISTRATION Erythromycin topical solution, 2% should be applied over the affected areas twice a day (morning and evening) after the skin is thoroughly washed with warm water and soap and patted dry. Acne lesions on the face, neck, shoulders, chest, and back may be treated in this manner. This medication should be applied with applicator top. If fingertips are used, wash hands after application. Drying and peeling may be controlled by reducing the frequency of applications.
Contraindications
CONTRAINDICATIONS Erythromycin topical solution, 2% is contraindicated in those individuals who have shown hypersensitivity to any of its components.
Warnings
WARNINGS Pseudomembranous colitis has been reported with nearly all antibacterial agents, including erythromycin, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Studies indicate that a toxin produced by Clostridium difficile is one primary cause of “antibiotic-associated colitis”. After the diagnosis of pseudomembranous colitis has been established, therapeutic measures should be initiated. Mild cases of pseudomembranous colitis usually respond to drug discontinuation alone. In moderate to severe cases, consideration should be given to management with fluids and electrolytes, protein supplementation and treatment with an antibacterial drug clinically effective against C. difficile colitis.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions have been reported occasionally: peeling, dryness, itching, erythema, and oiliness. Irritation of the eyes and tenderness of the skin have also been reported with topical use of erythromycin. Generalized urticarial reactions possibly related to the use of erythromycin, which required systemic steroid therapy have been reported. To report SUSPECTED ADVERSE REACTIONS, contact Saptalis Pharmaceuticals, LLC at 1-833-727-8254 or FDA at 1-­800‑FDA‑1088 or www.fda.gov/medwatch.
Use in pregnancy
Pregnancy There was no evidence of teratogenicity or any other adverse effect on reproduction in female rats fed erythromycin base (up to 0.25% of diet) prior to and during mating, during gestation and through weaning of two successive litters. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used in pregnancy only if clearly needed. Erythromycin has been reported to cross the placental barrier in humans, but fetal plasma levels are generally low.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.