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Gentamicin

Generic: GENTAMICIN SULFATE

Verified·Apr 23, 2026
Manufacturer
Schering
NDC
63187-560
RxCUI
313996
Route
INTRAMUSCULAR
ICD-10 indication
A41.9

Affordability Check

How much will you actually pay for Gentamicin?

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About Gentamicin

What is this medication? Gentamicin is a potent aminoglycoside antibiotic primarily prescribed to treat severe or life-threatening bacterial infections. It works by inhibiting protein synthesis within bacterial cells, which effectively stops the growth of the bacteria and leads to their destruction. This medication is typically reserved for serious infections caused by aerobic gram-negative bacteria, such as Pseudomonas, Proteus, and Escherichia coli, though it may also be used against certain gram-positive strains like Staphylococcus.

Doctors commonly use this medication to treat conditions such as sepsis, complicated urinary tract infections, meningitis, and infections of the respiratory tract, skin, or bones. It can be administered through various methods depending on the severity and location of the infection, including intravenous injections, intramuscular shots, or topical creams and eye drops. Because gentamicin has the potential to affect kidney function and hearing, healthcare providers usually monitor a patient’s blood levels and organ function closely during the course of treatment.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Prescribing information

From the FDA-approved label for Gentamicin. Official source: DailyMed (NLM) · Label effective Jun 1, 2022

Indications and usage
INDICATIONS AND USAGE Gentamicin sulfate ophthalmic solution is indicated in the topical treatment of ocular bacterial infections including conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus pneumoniae, Enterobacter aerogenes, Escherichia coli; Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens.
Dosage and administration
DOSAGE AND ADMINISTRATION Instill one or two drops into the affected eye(s) every four hours. In severe infections dosage may be increased to as much as two drops every hour.
Contraindications
CONTRAINDICATIONS Gentamicin sulfate ophthalmic solution is contraindicated in patients with known hypersensitivity to any of its components.
Warnings
WARNINGS NOT FOR INJECTION INTO THE EYE. Gentamicin sulfate ophthalmic solution is not for injection. It should never be injected subconjunctivally, nor should it be directly introduced into the anterior chamber of the eye.
Adverse reactions
ADVERSE REACTIONS Bacterial and fungal corneal ulcers have developed during treatment with gentamicin ophthalmic preparations. The most frequently reported adverse reactions are ocular burning and irritation upon drug instillation, non-specific conjunctivitis, conjunctival epithelial defects and conjunctival hyperemia. Other adverse reactions which have occurred rarely are allergic reactions, thrombocytopenic purpura and hallucinations.
Use in pregnancy
Pregnancy: Pregnancy Category C. Gentamicin has been shown to depress body weights, kidney weights and median glomerular counts in newborn rats when administered systemically to pregnant rats in daily doses approximately 500 times the maximum recommended ophthalmic human dose. There are no adequate and well-controlled studies in pregnant women. Gentamicin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Gentamicin appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

69%

3,801 of 5,509 plans

Most common tier

Tier 2

On 31% of covering formularies

Prior authorization required

6%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)73
22%
Tier 2 (generic)101
31%
Tier 3 (preferred brand)87
26%
Tier 4 (non-preferred brand)67
20%
Tier 61
0%

Step therapy: 0% of formularies

Quantity limits: 26% of formularies

Coverage breadth: 329 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.