How much does Hydrocortisone cost?

Pricing for Hydrocortisone varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Hydrocortisone need prior authorization?

Hydrocortisone appears on 3 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Hydrocortisone?

Yes — the manufacturer copay card link is available on this page. A patient assistance program is also available for qualifying patients. Eligibility typically depends on insurance type and income. Click the CTA buttons above to apply directly through the manufacturer's portal.

What is Hydrocortisone used to treat?

Hydrocortisone (generic: Hydrocortisone) is indicated for Dermatitis, Psoriasis, Addison's Disease and 4 other conditions. Click any condition name on this page for more detail.

Hydrocortisone

Generic: Hydrocortisone

Verified·Apr 23, 2026

Manufacturer: Pfizer
NDC: 55910-504
RxCUI: 106258
Route: TOPICAL
ICD-10 indication: L20.9

Affordability Check

How much will you actually pay for Hydrocortisone?

In 30 seconds, see every legitimate way to afford Hydrocortisone — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

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About Hydrocortisone

What is this medication? Hydrocortisone is a medication classified as a corticosteroid that is used to treat a wide variety of medical conditions. It works by reducing inflammation in the body and suppressing an overactive immune system response. Doctors commonly prescribe it to address skin issues like eczema, psoriasis, and severe allergic reactions. It is also effective in managing symptoms of inflammatory conditions such as arthritis, bowel disease, and certain types of asthma.

This medication can be administered in several forms, including tablets, injections, and topical creams, depending on the specific health concern. Beyond treating inflammation, hydrocortisone is frequently used as a hormone replacement therapy for patients whose adrenal glands do not produce enough natural cortisol. By mimicking the effects of this essential hormone, the medication helps maintain proper blood pressure, blood sugar levels, and metabolic functions throughout the body.

Copay & patient assistance

Patient Copay Amount: Not Publicly Available
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Not Publicly Available
RxBIN, PCN, and Group numbers: Not Publicly Available

Copay card →Patient Assistance Program →

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Hydrocortisone.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Hydrocortisone →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Hydrocortisone →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Hydrocortisone. Official source: DailyMed (NLM) · Label effective Nov 15, 2024

Indications and usage

Uses • temporarily relieves itching associated with minor skin irritations, inflammation, and rashes due to: • eczema • psoriasis • poison ivy, oak, sumac • insect bites • detergents • jewelry • cosmetics • soaps • seborrheic dermatitis • temporarily relieves external anal and genital itching • other uses of this product should be only under the advice and supervision of a doctor

Dosage and administration

Directions • for itching of skin irritation, inflammation, and rashes: • adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times daily • children under 2 years of age: do not use, ask a doctor • for external anal and genital itching, adults: • when practical, clean the affected area with mild soap and warm water and rinse thoroughly • gently dry by patting or blotting with toilet tissue or a soft cloth before applying • apply to affected area not more than 3 to 4 times daily • children under 12 years of age: ask a doctor

Warnings

Warnings For external use only Do not use • in the genital area if you have a vaginal discharge. Ask a doctor. • for the treatment of diaper rash. Ask a doctor. When using this product • avoid contact with the eyes • do not use more than directed unless told to do so by a doctor • do not put directly into the rectum by using fingers or any mechanical device or applicator Stop use and ask a doctor if • condition worsens • symptoms persist for more than 7 days or clear up and occur again within a few days, and do not begin use of any other hydrocortisone product unless you have asked a doctor • rectal bleeding occurs Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Hydrocortisone appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

37%

2,028 of 5,509 plans

Most common tier

Tier 4

On 48% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	52	19%
Tier 2 (generic)	70	26%
Tier 3 (preferred brand)	18	7%
Tier 4 (non-preferred brand)	129	48%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 269 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

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Medicare Part D

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Medicare Part D

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Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.