Hydrocortisone Cream
Generic: Hydrocortisone
- NDC
- 58228-2896
- RxCUI
- 106258
- Route
- TOPICAL
- ICD-10 indication
- L30.9
Affordability Check
How much will you actually pay for Hydrocortisone Cream?
In 30 seconds, see every legitimate way to afford Hydrocortisone Cream — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Hydrocortisone Cream
What is this medication?
Hydrocortisone cream is a topical corticosteroid used to treat a wide variety of skin conditions that cause inflammation, redness, and itching. It works by reducing the body's natural inflammatory response to irritants, allergens, or underlying medical issues. This medication is commonly prescribed to manage symptoms of skin problems such as dermatitis, eczema, and persistent rashes. It is intended for external use only and should be applied directly to the affected area as directed by a healthcare provider to ensure safety and effectiveness.
In addition to chronic conditions, hydrocortisone cream can provide temporary relief from minor skin irritations like insect bites, poison ivy, or allergic reactions to detergents and jewelry. By suppressing the local immune response, the cream helps to alleviate swelling and discomfort relatively quickly. While lower strengths of the cream are often available over the counter, higher concentrations require a prescription to treat more severe or stubborn cases of skin inflammation.
Copay & patient assistance
Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Hydrocortisone.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Hydrocortisone Cream →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for Hydrocortisone →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
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Prescribing information
From the FDA-approved label for Hydrocortisone Cream. Official source: DailyMed (NLM) · Label effective Dec 15, 2025
Indications and usage
Dosage and administration
Warnings
Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Hydrocortisone Cream appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).
Covered by plans
69%
3,777 of 5,509 plans
Most common tier
Tier 1
On 50% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 161 | 50% |
| Tier 2 (generic) | 159 | 49% |
| Tier 3 (preferred brand) | 4 | 1% |
Step therapy: 0% of formularies
Quantity limits: 12% of formularies
Coverage breadth: 324 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
Related drugs
Texacort
Same generic · Hydrocortisone
Proctosol-HC
Same generic · Hydrocortisone
Procto-Med HC
Same generic · HYDROCORTISONE
Cortenema
Same generic · Hydrocortisone
Proctocort
Same generic · HYDROCORTISONE
Hydrocortisone
Same generic · Hydrocortisone
Duobrii
Treats same condition · halobetasol propionate and tazarotene
Calcipotriene
Treats same condition · calcipotriene
DERMOTIC
Treats same condition · fluocinolone acetonide
Trionex
Treats same condition · Calcipotriene Cream, 0.005% and Transparent Dressing
How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.