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Hydrocortisone Acetate Pramoxine Hcl

Generic: Hydrocortisone Acetate Pramoxine Hcl

Verified·Apr 23, 2026
Manufacturer
Sebela Pharmaceuticals
NDC
71335-2939
RxCUI
1294025
Route
TOPICAL
ICD-10 indication
L30.9

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About Hydrocortisone Acetate Pramoxine Hcl

Hydrocortisone acetate and pramoxine hydrochloride is a combination prescription medicine used to treat swelling, itching, and pain caused by skin or rectal conditions. The hydrocortisone component belongs to a class of drugs known as corticosteroids, which function by lowering the body's inflammatory response to reduce redness and swelling. This medication is frequently prescribed for conditions such as hemorrhoids, anal pruritus, or various types of dermatitis where localized discomfort and inflammation are present. The pramoxine hydrochloride in this medication serves as a local anesthetic that numbs the area by interfering with pain signals sent from the nerves to the brain. This provides fast relief from the persistent itching or stinging sensations that often accompany inflammatory skin conditions. By combining an anti-inflammatory agent with a topical numbing agent, the medication provides a dual approach to managing symptoms. It is typically available in forms such as creams or lotions for direct application to the affected area.

Copay & patient assistance

  • Patient Copay Amount: As little as $10 out-of-pocket costs for many eligible patients
  • Maximum Annual Benefit Limit: Not Publicly Available (Note: Offer includes unlimited refills)
  • Core Eligibility Restrictions: Coupon not valid for prescriptions reimbursed in whole or in part under Medicaid, Medicare (including Medicare Advantage and Part D prescription drug plans), or any other federal or state program (including state pharmaceutical assistance programs). Offer good only in the USA at participating retail pharmacies and cannot be redeemed at government-subsidized clinics. Offer may not be combined with any other rebate, coupon, free trial, or similar offer.
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Hydrocortisone Acetate Pramoxine Hcl. Official source: DailyMed (NLM) · Label effective Oct 24, 2025

Indications and usage
INDICATIONS AND USAGE Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Folliculitis Hypertrichosis Acneiform eruptions Hypopigmentation Perioral dermatitis Allergic contact dermatitis Maceration of the skin Secondary infection Skin atrophy Striae Miliaria
Use in pregnancy
Pregnancy Teratogenic Effects: Pregnancy Category C – Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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Medicare Part D

Medicare Part D

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.