Icosapent
Generic: icosapent ethyl
- Manufacturer
- Amarin
- NDC
- 35916-1592
- RxCUI
- 1304979
- Route
- ORAL
- ICD-10 indication
- E78.1
Affordability Check
How much will you actually pay for Icosapent?
In 30 seconds, see every legitimate way to afford Icosapent — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Icosapent
What is this medication?
Icosapent ethyl is a prescription medication that consists of a highly purified form of eicosapentaenoic acid, which is an omega-3 fatty acid derived from fish oil. It is primarily used to treat adults who have severely high triglyceride levels in their blood, a condition known as hypertriglyceridemia. By decreasing the amount of triglycerides produced by the liver and improving their removal from the blood, the medication helps prevent complications such as inflammation of the pancreas.
Beyond its use for lowering lipids, icosapent ethyl is also prescribed to reduce the risk of cardiovascular events including heart attacks, strokes, and the need for certain heart procedures. It is typically used in combination with a low-fat diet and statin therapy for patients who have established heart disease or diabetes along with other cardiovascular risk factors. Because it contains only purified EPA without other types of fish oils, it does not raise low-density lipoprotein cholesterol levels while it works to protect heart health.
Copay & patient assistance
- Patient Copay Amount: As little as $9 for a 90-day supply; patient pays the first $9 after insurer's payment.
- Maximum Annual Benefit Limit: $2,250 annually (up to $150 per 1-month fill or $450 per 3-month fill).
- Core Eligibility Restrictions: Valid for adults with commercial insurance or cash-paying uninsured patients; not valid for patients enrolled in Medicare, Medicaid, TRICARE, or any other state- or federally-funded prescription drug programs; void in California (CA) and Massachusetts (MA).
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for icosapent ethyl.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Icosapent →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for icosapent ethyl →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Icosapent appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).
Covered by plans
34%
1,888 of 5,509 plans
Most common tier
Tier 4
On 32% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 53 | 26% |
| Tier 2 (generic) | 57 | 28% |
| Tier 3 (preferred brand) | 31 | 15% |
| Tier 4 (non-preferred brand) | 66 | 32% |
Step therapy: 0% of formularies
Quantity limits: 57% of formularies
Coverage breadth: 207 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.