Icosapent Ethyl
Generic: icosapent ethyl
- Manufacturer
- Amarin
- NDC
- 35916-1592
- RxCUI
- 1304979
- Route
- ORAL
- ICD-10 indication
- E78.1
Affordability Check
How much will you actually pay for Icosapent Ethyl?
In 30 seconds, see every legitimate way to afford Icosapent Ethyl — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Icosapent Ethyl
What is this medication?
Icosapent ethyl is a prescription medication that consists of a highly purified form of the omega-3 fatty acid known as eicosapentaenoic acid, or EPA. It is primarily used to lower very high levels of triglycerides in adults, which are a type of fat found in the blood. When triglyceride levels are 500 mg/dL or higher, they can increase the risk of developing pancreatitis. This medication is typically used in conjunction with a low-fat and low-cholesterol diet to help patients manage these lipid levels effectively.
Beyond lowering triglycerides, icosapent ethyl is also approved to reduce the risk of heart attack, stroke, and certain types of heart surgery in specific high-risk patients. This includes adults who have established cardiovascular disease or those with diabetes and multiple other risk factors for heart disease. It is meant to be taken alongside a statin, which is another type of cholesterol-lowering drug. Unlike many common fish oil supplements, this medication is a purified form of EPA and does not include DHA, ensuring it does not raise low-density lipoprotein cholesterol levels.
Copay & patient assistance
- Patient Copay Amount: As little as $9 for a 90-day supply (approximately $3 per month); patient pays the first $9 of the prescription cost.
- Maximum Annual Benefit Limit: $2,250 per calendar year (maximum savings of $150 per 1-month fill or $450 per 3-month fill).
- Core Eligibility Restrictions: Offer is valid for adult patients with a valid prescription; must have commercial insurance or be a cash-paying uninsured patient; patients enrolled in Medicare, Medicaid, TRICARE, or any other federal or state-funded healthcare program are ineligible; offer is void in California (CA) and Massachusetts (MA).
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for icosapent ethyl.
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GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Icosapent Ethyl →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for icosapent ethyl →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
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Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Icosapent Ethyl appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).
Covered by plans
34%
1,888 of 5,509 plans
Most common tier
Tier 4
On 32% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 53 | 26% |
| Tier 2 (generic) | 57 | 28% |
| Tier 3 (preferred brand) | 31 | 15% |
| Tier 4 (non-preferred brand) | 66 | 32% |
Step therapy: 0% of formularies
Quantity limits: 57% of formularies
Coverage breadth: 207 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
Related drugs
Icosapent
Same generic · icosapent ethyl
Vascepa
Same generic · icosapent ethyl
Tricor
Treats same condition · Fenofibrate
FENOFIBRATE
Treats same condition · Fenofibrate
Myalept
Treats same condition · metreleptin
Niacin
Treats same condition · niacin
Lovaza
Treats same condition · OMEGA-3-ACID ETHYL ESTERS
JAVYGTOR
Treats same condition · Sapropterin Dihydrochloride
Rosuvastatin
Treats same condition · Rosuvastatin
FENOFIBRIC ACID DELAYED-RELEASE
Treats same condition · FENOFIBRIC ACID
How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.