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Irinotecan Hydrochloride 40 mg/2 mL

Verified·Apr 23, 2026
Manufacturer
Pfizer
NDC
72485-211
ICD-10 indication
C18.9

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About Irinotecan Hydrochloride 40 mg/2 mL

What is this medication? Irinotecan hydrochloride is a chemotherapy drug specifically indicated for the treatment of patients with metastatic cancer of the colon or rectum. It is commonly used as a first-line therapy in combination with other anti-cancer medications or as a single agent for patients whose cancer has returned or progressed after receiving initial treatments. The 40 mg/2 mL formulation is a concentrated liquid meant to be diluted and administered through an intravenous infusion by a healthcare professional.

The medication belongs to a class of drugs known as topoisomerase I inhibitors. It works by targeting and blocking an enzyme that cancer cells need to copy their DNA, which is a necessary step for the cells to divide and grow. By interrupting this process, the medication helps slow down or stop the spread of the disease. Because it is a potent systemic treatment, it is administered in a clinical setting where medical staff can monitor the patient for response and potential side effects during the treatment cycle.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Conditions we've indexed resources for

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Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.