LMD in Dextrose, LMD in Sodium Chloride

What is this medication? LMD in Dextrose and LMD in Sodium Chloride are sterile solutions containing low molecular weight dextran, specifically dextran 40. These medications are classified as plasma volume expanders and are primarily used as adjunctive therapy in the treatment of shock or impending shock. This condition may be caused by hemorrhage, burns, surgery, or other trauma where a rapid expansion of plasma volume is necessary. By drawing fluid from the interstitial space into the blood vessels, these solutions help restore blood pressure and improve systemic circulation during emergency medical situations.

In addition to volume expansion, these medications are used to improve blood flow through the smallest blood vessels, a process known as microcirculation. Dextran 40 works by reducing the viscosity of the blood and preventing red blood cells from clumping together. This property makes it useful for certain vascular surgical procedures to help prevent the formation of blood clots or to improve blood flow in conditions where circulation is compromised. The choice between the dextrose or sodium chloride version depends on the patient's individual electrolyte and fluid balance needs as determined by a healthcare provider.