LOPERAMIDE HYDROCHLORIDE
Generic: Loperamide Hydrochloride
- Manufacturer
- Janssen
- NDC
- 80136-384
- RxCUI
- 978006
- Route
- ORAL
- ICD-10 indication
- R19.7
Affordability Check
How much will you actually pay for LOPERAMIDE HYDROCHLORIDE?
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About LOPERAMIDE HYDROCHLORIDE
What is this medication?
Loperamide hydrochloride is a medication primarily used to treat sudden diarrhea, including traveler's diarrhea. It functions by slowing the rhythm of digestion, which allows the intestines more time to absorb water and electrolytes from the waste passing through the body. This process leads to firmer stools and a significant decrease in the frequency of bowel movements for the patient.
This medication is also frequently prescribed for individuals who have had an ileostomy to help reduce the volume of intestinal output. While loperamide hydrochloride effectively manages the symptoms of diarrhea, it is not an antibiotic and will not treat infections caused by bacteria or parasites. It should be used according to the specific dosage instructions provided by a healthcare professional to ensure safety and effectiveness.
Copay & patient assistance
Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Loperamide Hydrochloride.
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GoodRx
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Lookup LOPERAMIDE HYDROCHLORIDE →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
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RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
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Prescribing information
From the FDA-approved label for LOPERAMIDE HYDROCHLORIDE. Official source: DailyMed (NLM) · Label effective Jan 7, 2025
Indications and usage
Dosage and administration
Warnings
Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How LOPERAMIDE HYDROCHLORIDE appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).
Covered by plans
71%
3,901 of 5,509 plans
Most common tier
Tier 2
On 67% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 91 | 28% |
| Tier 2 (generic) | 218 | 67% |
| Tier 3 (preferred brand) | 18 | 6% |
Step therapy: 0% of formularies
Quantity limits: 0% of formularies
Coverage breadth: 327 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
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How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.