How much does Naftifine Hydrochloride cost?

Pricing for Naftifine Hydrochloride varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Naftifine Hydrochloride need prior authorization?

Naftifine Hydrochloride appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Naftifine Hydrochloride?

We haven't verified an active copay card or PAP for Naftifine Hydrochloride in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Naftifine Hydrochloride used to treat?

Naftifine Hydrochloride (generic: Naftifine Hydrochloride) is indicated for Ringworm. Click any condition name on this page for more detail.

Naftifine Hydrochloride

Generic: Naftifine Hydrochloride

Verified·Apr 23, 2026

Manufacturer: Sebela
NDC: 51672-1362
ICD-10 indication: B35.9

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About Naftifine Hydrochloride

What is this medication? Naftifine hydrochloride is a prescription antifungal medication used to treat fungal skin infections. It is specifically formulated to address conditions such as tinea pedis, commonly known as athlete's foot, as well as tinea cruris, known as jock itch, and tinea corporis, known as ringworm. As an allylamine antifungal, it works by interfering with the synthesis of sterols in the fungi, which ultimately prevents the fungus from growing and spreading across the skin's surface.

The medication is applied topically as a cream or gel to the infected area, typically once or twice a day as directed by a healthcare provider. By targeting the fungal cell membranes, naftifine hydrochloride helps to relieve the discomfort associated with these infections, including redness, peeling, and intense itching. It is essential for patients to complete the full course of treatment even if the skin appears to be healing to ensure that the infection does not recur.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Naftifine Hydrochloride.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Naftifine Hydrochloride →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Naftifine Hydrochloride →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Naftifine Hydrochloride. Official source: DailyMed (NLM) · Label effective Jul 7, 2025

Indications and usage

INDICATIONS AND USAGE Naftifine Hydrochloride Cream USP, 1% is indicated for the topical treatment of tinea pedis, tinea cruris and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum .

Dosage and administration

DOSAGE AND ADMINISTRATION A sufficient quantity of Naftifine Hydrochloride Cream USP, 1% should be gently massaged into the affected and surrounding skin areas once a day. The hands should be washed after application. If no clinical improvement is seen after four weeks of treatment with Naftifine Hydrochloride Cream USP, 1%, the patient should be re-evaluated.

Contraindications

CONTRAINDICATIONS Naftifine Hydrochloride Cream USP, 1% is contraindicated in individuals who have shown hypersensitivity to any of its components.

Warnings

WARNINGS Naftifine Hydrochloride Cream USP, 1% is for topical use only and not for ophthalmic use.

Adverse reactions

ADVERSE REACTIONS During clinical trials with Naftifine Hydrochloride Cream USP, 1%, the incidence of adverse reactions was as follows: burning/stinging (6%), dryness (3%), erythema (2%), itching (2%), local irritation (2%).

Use in pregnancy

Pregnancy Teratogenic Effects Reproduction studies have been performed in rats and rabbits (via oral administration) at doses 150 times or more than the topical human dose and have revealed no evidence of impaired fertility or harm to the fetus due to naftifine. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Ringworm

Medicare Part D coverage

How Naftifine Hydrochloride appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

15%

806 of 5,509 plans

Most common tier

Tier 4

On 70% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	10	20%
Tier 2 (generic)	3	6%
Tier 3 (preferred brand)	2	4%
Tier 4 (non-preferred brand)	35	70%

Step therapy: 2% of formularies

Quantity limits: 68% of formularies

Coverage breadth: 50 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.