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Oxistat

Generic: oxiconazole nitrate

Verified·Apr 23, 2026
Manufacturer
PharmaDerm
NDC
62559-285
RxCUI
207249
Route
TOPICAL
ICD-10 indication
B35.9

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About Oxistat

What is this medication? Oxistat is a topical antifungal medication used to treat various types of skin infections caused by fungi. The active ingredient, oxiconazole nitrate, works by weakening the cell membranes of the fungi, which prevents them from growing and spreading. This medication is available by prescription and is typically found in either cream or lotion forms for direct application to the infected area of the skin. Healthcare providers commonly prescribe Oxistat to address conditions such as tinea pedis, tinea cruris, and tinea corporis, which are more widely known as athletes foot, jock itch, and ringworm. It is also used to treat tinea versicolor, a fungal infection that creates light or dark patches on the chest, back, or arms. Patients usually apply the medication once or twice daily for several weeks to ensure the infection is completely eradicated and to prevent it from returning.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Oxistat. Official source: DailyMed (NLM) · Label effective Jul 24, 2025

Indications and usage
INDICATIONS AND USAGE OXISTAT Lotion is indicated for the topical treatment of the following dermal infections: tinea pedis, tinea cruris, and tinea corporis due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum (see DOSAGE AND ADMINISTRATION and CLINICAL STUDIES ).
Dosage and administration
DOSAGE AND ADMINISTRATION OXISTAT Lotion should be applied to affected and immediately surrounding areas once to twice daily in patients with tinea pedis, tinea corporis, or tinea cruris. Tinea corporis and tinea cruris should be treated for 2 weeks and tinea pedis for 1 month to reduce the possibility of recurrence. If a patient shows no clinical improvement after the treatment period, the diagnosis should be reviewed.
Contraindications
CONTRAINDICATIONS OXISTAT Lotion is contraindicated in individuals who have shown hypersensitivity to any of their components.
Warnings
WARNINGS OXISTAT (oxiconazole nitrate) Lotion, 1% is for topical use only and not for oral, ophthalmic or intravaginal use.
Drug interactions
Drug Interactions Potential drug interactions between OXISTAT and other drugs have not been systematically evaluated.
Adverse reactions
ADVERSE REACTIONS In a controlled, multicenter clinical trial of 269 patients treated with oxiconazole nitrate lotion , 1%, 7 (2.6%) reported adverse reactions thought to be related to drug therapy. These reactions included burning and stinging (0.7% each) and pruritus, scaling, tingling, pain, and dyshidrotic eczema (0.4% each). The following additional adverse experiences have been reported with the topical use of oxiconazole nitrate: irritation and allergic contact dermatitis, folliculitis, erythema, papules, fissure, maceration, rash, and nodules. To report SUSPECTED ADVERSE REACTIONS, contact ANI Pharmaceuticals, Inc. at 1-800-308-6755 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Use in pregnancy
Pregnancy Teratogenic Effects Reproduction studies have been performed in rabbits, rats, and mice at oral doses up to 100, 150, and 200 mg/kg/day (57, 40, and 27 times the human dose based on mg/m 2 ), respectively, and revealed no evidence of harm to the fetus due to oxiconazole nitrate. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Oxistat appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

1%

52 of 5,509 plans

Most common tier

Tier 4

On 67% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 2 (generic)1
33%
Tier 4 (non-preferred brand)2
67%

Step therapy: 33% of formularies

Quantity limits: 67% of formularies

Coverage breadth: 3 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.