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NYSTATIN AND TRIAMCINOLONE ACETONIDE

Generic: nystatin and triamcinolone acetonide

Verified·Apr 23, 2026
NDC
51672-1272
RxCUI
1053697
Route
TOPICAL
ICD-10 indication
B37.2

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About NYSTATIN AND TRIAMCINOLONE ACETONIDE

What is this medication? Nystatin and triamcinolone acetonide is a combination topical medication used to treat skin infections caused by fungus or yeast, particularly those involving Candida. This treatment contains two active components that work in tandem to resolve the skin condition. Nystatin is an antifungal agent that functions by stopping the growth of the fungus responsible for the infection. Triamcinolone acetonide is a medium-strength corticosteroid that focuses on reducing the inflammatory response, effectively easing symptoms like redness, swelling, and persistent itching. Doctors often prescribe this combination for cutaneous candidiasis, which frequently develops in warm, moist areas of the body such as skin folds. By using both an antifungal and a steroid together, the medication offers quicker relief from physical discomfort while addressing the source of the infection. It should be applied as a thin layer to the affected skin according to a healthcare provider's instructions. Patients should typically avoid covering the treated area with airtight bandages and should complete the full course of treatment even if symptoms improve early.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for NYSTATIN AND TRIAMCINOLONE ACETONIDE. Official source: DailyMed (NLM) · Label effective Jul 7, 2025

Indications and usage
INDICATIONS AND USAGE Nystatin and Triamcinolone Acetonide Cream and Ointment are indicated for the treatment of cutaneous candidiasis; it has been demonstrated that the nystatin-steroid combination provides greater benefit than the nystatin component alone during the first few days of treatment.
Dosage and administration
DOSAGE AND ADMINISTRATION Nystatin and Triamcinolone Acetonide Cream is usually applied to the affected areas twice daily in the morning and evening by gently and thoroughly massaging the preparation into the skin. The cream should be discontinued if symptoms persist after 25 days of therapy (see PRECAUTIONS, Laboratory Tests ). A thin film of Nystatin and Triamcinolone Acetonide Ointment is usually applied to the affected areas twice daily in the morning and evening. The preparation should be discontinued if symptoms persist after 25 days of therapy (see PRECAUTIONS, Laboratory Tests ). Nystatin and Triamcinolone Acetonide Cream and Ointment should not be used with occlusive dressings.
Contraindications
CONTRAINDICATIONS These preparations are contraindicated in those patients with a history of hypersensitivity to any of their components.
Adverse reactions
ADVERSE REACTIONS A single case (approximately one percent of patients studied) of acneiform eruption occurred with use of combined nystatin and triamcinolone acetonide in clinical studies. Nystatin is virtually nontoxic and nonsensitizing and is well tolerated by all age groups, even during prolonged use. Rarely, irritation may occur. The following local adverse reactions are reported infrequently with topical corticosteroids (reactions are listed in an approximate decreasing order of occurrence): burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, perioral secondary infection, skin atrophy, striae and miliaria.
Use in pregnancy
Pregnancy Category C There are no teratogenic studies with combined nystatin and triamcinolone acetonide. Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. Therefore, any topical corticosteroid preparation should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Topical preparations containing corticosteroids should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How NYSTATIN AND TRIAMCINOLONE ACETONIDE appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

44%

2,408 of 5,509 plans

Most common tier

Tier 2

On 35% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)71
32%
Tier 2 (generic)79
35%
Tier 3 (preferred brand)29
13%
Tier 4 (non-preferred brand)45
20%

Step therapy: 0% of formularies

Quantity limits: 33% of formularies

Coverage breadth: 224 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Medicare Part D

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.