How much does Nystatin Topical Powder cost?

Pricing for Nystatin Topical Powder varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Nystatin Topical Powder need prior authorization?

Nystatin Topical Powder appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Nystatin Topical Powder?

We haven't verified an active copay card or PAP for Nystatin Topical Powder in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Nystatin Topical Powder used to treat?

Nystatin Topical Powder is indicated for Candidiasis, Cutaneous Candidiasis. Click any condition name on this page for more detail.

Nystatin Topical Powder

Verified·Apr 23, 2026

NDC: 42806-178
ICD-10 indication: B37.2

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About Nystatin Topical Powder

What is this medication?

Nystatin topical powder is a prescription antifungal medicine used to treat various types of skin infections caused by yeast, specifically those involving Candida species. This medication works by stopping the growth of the fungus, which helps to clear the infection and relieve associated symptoms like itching, redness, or burning. It is most commonly prescribed for fungal infections occurring in moist areas of the body, such as the groin, skin folds, or between the toes.

The powder formulation is particularly beneficial for treating cutaneous yeast infections because it helps absorb excess moisture in the affected area, creating an environment that is less favorable for fungal growth. Patients typically apply the powder to the clean, dry skin area two to three times a day or as directed by a healthcare provider. It is important to complete the entire course of treatment even if symptoms improve quickly to ensure the infection is fully eradicated and does not return.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Nystatin Topical Powder.

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GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

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NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

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RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

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We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Nystatin Topical Powder. Official source: DailyMed (NLM) · Label effective May 2, 2018

Indications and usage

INDICATIONS AND USAGE Nystatin topical powder is indicated in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species. Nystatin topical powder is not indicated for systemic, oral, intravaginal or ophthalmic use.

Dosage and administration

DOSAGE AND ADMINISTRATION Very moist lesions are best treated with the topical dusting powder. Adults and Pediatric Patients (Neonates and Older) Apply to candidal lesions two or three times daily until healing is complete. For fungal infection of the feet caused by Candida species, the powder should be dusted on the feet, as well as, in all foot wear.

Contraindications

CONTRAINDICATIONS Nystatin topical powder is contraindicated in patients with a history of hypersensitivity to any of its components.

Adverse reactions

ADVERSE REACTIONS The frequency of adverse events reported in patients using nystatin topical powder is less than 0.1%. The more common events that were reported include allergic reactions, burning, itching, rash, eczema, and pain on application. (See PRECAUTIONS, General .)

Use in pregnancy

Pregnancy Teratogenic Effects Category C Animal reproduction studies have not been conducted with any nystatin topical preparation. It also is not known whether these preparations can cause fetal harm when used by a pregnant woman or can affect reproductive capacity. Nystatin topical powder should be prescribed for a pregnant woman only if the potential benefit to the mother outweighs the potential risk to the fetus.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

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Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.