Orladeyo

What is this medication? Orladeyo is a prescription medicine used to prevent attacks of hereditary angioedema (HAE) in adults and children 12 years of age and older. HAE is a rare genetic disorder characterized by sudden and severe swelling in different parts of the body, such as the hands, feet, face, and throat. This medication is taken orally as a once-daily capsule to help reduce the frequency of these painful and potentially dangerous swelling episodes over time.

The active ingredient in Orladeyo is berotralstat, which belongs to a class of drugs known as plasma kallikrein inhibitors. It works by blocking the activity of an enzyme called plasma kallikrein, which helps control the levels of a protein that triggers swelling. It is important to note that Orladeyo is intended for long-term prevention and should not be used to treat an acute HAE attack that is already occurring.