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Pepcid

Generic: famotidine

Verified·Apr 23, 2026
Manufacturer
Merck
NDC
66715-6422
RxCUI
104094
Route
ORAL
ICD-10 indication
K21.9

Affordability Check

How much will you actually pay for Pepcid?

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About Pepcid

What is this medication? Pepcid, which contains the active ingredient famotidine, is a medication classified as an H2 blocker or histamine-2 antagonist. Its primary function is to decrease the amount of acid produced by the stomach. Doctors typically prescribe this medication to treat and prevent various conditions of the gastrointestinal tract, such as stomach and intestinal ulcers. It is also highly effective for managing gastroesophageal reflux disease, commonly known as GERD, which occurs when stomach acid flows back into the esophagus and causes irritation.

In addition to treating active ulcers and acid reflux, this medication is used to manage conditions where the stomach produces excessive amounts of acid, such as Zollinger-Ellison syndrome. It can also help relieve and prevent symptoms of heartburn associated with acid indigestion or a sour stomach. By reducing the overall acidity in the digestive system, the medication allows the lining of the esophagus and stomach to heal and protects them from further damage caused by corrosive gastric fluids.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Prescribing information

From the FDA-approved label for Pepcid. Official source: DailyMed (NLM) · Label effective Jan 25, 2024

Indications and usage
Use relieves heartburn associated with acid indigestion and sour stomach
Dosage and administration
Directions adults and children 12 years and over: do not swallow tablet whole: chew completely to relieve symptoms, chew 1 tablet before swallowing. do not use more than 2 chewable tablets in 24 hours children under 12 years: ask a doctor
Warnings
Warnings Allergy alert: Do not use if you are allergic to famotidine or other acid reducers Do not use if you have trouble or pain swallowing food, vomiting with blood, or bloody or black stools. These may be signs of a serious condition. See your doctor. with other acid reducers Ask a doctor before use if you have had heartburn over 3 months. This may be a sign of a more serious condition. heartburn with lightheadedness, sweating, or dizziness chest pain or shoulder pain with shortness of breath; sweating; pain spreading to arms, neck or shoulders; or lightheadedness frequent chest pain frequent wheezing, particularly with heartburn unexplained weight loss nausea or vomiting stomach pain kidney disease Ask a doctor or pharmacist before use if you are taking a prescription drug. Antacids and acid reducers may interact with certain prescription drugs. Stop use and ask a doctor if your heartburn continues or worsens you need to take this product for more than 14 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Allergy alert: Do not use if you are allergic to famotidine or other acid reducers

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Pepcid appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

0%

1 of 5,509 plans

Most common tier

Tier 1

On 100% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)1
100%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 1 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.