How much does Phenoxybenzamine Hydrochloride cost?

Pricing for Phenoxybenzamine Hydrochloride varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Phenoxybenzamine Hydrochloride need prior authorization?

Phenoxybenzamine Hydrochloride appears on 3 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Phenoxybenzamine Hydrochloride?

We haven't verified an active copay card or PAP for Phenoxybenzamine Hydrochloride in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Phenoxybenzamine Hydrochloride used to treat?

Phenoxybenzamine Hydrochloride (generic: PHENOXYBENZAMINE HYDROCHLORIDE) is indicated for Hypertension, Benign Adrenal Gland Tumor, Adrenal Cancer and 3 other conditions. Click any condition name on this page for more detail.

Phenoxybenzamine Hydrochloride

Generic: PHENOXYBENZAMINE HYDROCHLORIDE

Verified·Apr 23, 2026

Manufacturer: Advanz
NDC: 70954-365
ICD-10 indication: C74.10

Affordability Check

How much will you actually pay for Phenoxybenzamine Hydrochloride?

In 30 seconds, see every legitimate way to afford Phenoxybenzamine Hydrochloride — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

Check my options →

About Phenoxybenzamine Hydrochloride

What is this medication? Phenoxybenzamine Hydrochloride is an alpha-adrenergic blocker primarily used to manage high blood pressure and sweating in patients with pheochromocytoma. This medical condition involves a tumor on the adrenal gland that releases excessive amounts of hormones like adrenaline and noradrenaline. By blocking specific receptors in the blood vessels, the medication helps stabilize blood pressure levels and is most frequently prescribed to prepare patients for surgery to remove the tumor.

The medication works by relaxing and widening the blood vessels, which allows blood to flow more easily and reduces the workload on the heart. Beyond its use before surgery, it may also be employed for the long-term management of symptoms when a tumor cannot be surgically removed. Because the drug can cause a significant drop in blood pressure when changing positions, patients are typically monitored closely by their healthcare provider to ensure the dosage is safe and effective.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for PHENOXYBENZAMINE HYDROCHLORIDE.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Phenoxybenzamine Hydrochloride →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for PHENOXYBENZAMINE HYDROCHLORIDE →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Phenoxybenzamine Hydrochloride. Official source: DailyMed (NLM) · Label effective Oct 18, 2022

Indications and usage

INDICATIONS & USAGE Phenoxybenzamine Hydrochloride Capsules are indicated in the treatment of pheochromocytoma, to control episodes of hypertension and sweating. If tachycardia is excessive, it may be necessary to use a beta -blocking agent concomitantly.

Dosage and administration

DOSAGE & ADMINISTRATION The dosage should be adjusted to fit the needs of each patient. Small initial doses should be slowly increased until the desired effect is obtained or the side effects from blockade become troublesome. After each increase, the patient should be observed on that level before instituting another increase. The dosage should be carried to a point where symptomatic relief and/or objective improvement are obtained, but not so high that the side effects from blockade become troublesome. Initially, 10 mg of phenoxybenzamine hydrochloride twice a day. Dosage should be increased every other day, usually to 20 to 40 mg 2 or 3 times a day, until an optimal dosage is obtained, as judged by blood pressure control. Long-term use of phenoxybenzamine is not recommended (see PRECAUTIONS Carcinogenesis and Mutagenesis).

Contraindications

CONTRAINDICATIONS Conditions where a fall in blood pressure may be undesirable; hypersensitivity to the drug or any of its components.

Warnings

WARNINGS Phenoxybenzamine hydrochloride-induced alpha -adrenergic blockade leaves beta -adrenergic receptors unopposed. Compounds that stimulate both types of receptors may, therefore, produce an exaggerated hypotensive response and tachycardia.

Drug interactions

DRUG INTERACTIONS Phenoxybenzamine hydrochloride may interact with compounds that stimulate both alpha - and beta -adrenergic receptors (i.e., epinephrine) to produce an exaggerated hypotensive response and tachycardia. (See WARNINGS.) Phenoxybenzamine hydrochloride blocks hyperthermia production by levarterenol, and blocks hypothermia production by reserpine.

Adverse reactions

ADVERSE REACTIONS The following adverse reactions have been observed, but there are insufficient data to support an estimate of their frequency. Autonomic Nervous System*: Postural hypotension, tachycardia, inhibition of ejaculation, nasal congestion, miosis. *These so-called "side effects" are actually evidence of adrenergic blockade and vary according to the degree of blockade. Miscellaneous: Gastrointestinal irritation, drowsiness, fatigue. To report SUSPECTED ADVERSE REACTIONS, contact Novitium Pharma, LLC at 1-855-204-1431 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Use in pregnancy

PREGNANCY Teratogenic Effects Adequate reproductive studies in animals have not been performed with phenoxybenzamine hydrochloride. It is also not known whether phenoxybenzamine hydrochloride can cause fetal harm when administered to a pregnant woman. Phenoxybenzamine hydrochloride should be given to a pregnant woman only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Phenoxybenzamine Hydrochloride appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

14%

762 of 5,509 plans

Most common tier

Tier 5

On 87% of covering formularies

Prior authorization required

27%

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	8	11%
Tier 2 (generic)	1	1%
Tier 4 (non-preferred brand)	1	1%
Tier 5 (specialty)	65	87%

Step therapy: 0% of formularies

Quantity limits: 3% of formularies

Coverage breadth: 75 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Medicare Part D

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.