Plasma-Lyte 148 (pH 7.4)

What is this medication? Plasma-Lyte 148 (pH 7.4) is a sterile, nonpyrogenic isotonic solution designed for intravenous administration. It contains a specific blend of electrolytes, including sodium, potassium, magnesium, chloride, acetate, and gluconate, formulated to closely resemble the chemical composition of human blood plasma. Because the pH is adjusted to approximately 7.4, it is considered a balanced crystalloid solution that helps maintain normal physiological acid-base levels when administered to patients.

This medication is primarily used to replace lost fluids and electrolytes in patients who are dehydrated or undergoing surgery. It is frequently utilized for short-term volume depletion or as a source of water and electrolytes when a patient is unable to take them orally. Additionally, healthcare providers use it to treat certain types of metabolic acidosis because the acetate and gluconate components are metabolized into bicarbonate, which helps neutralize excess acid in the body.