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Plasma-Lyte 148 (pH 7.4)

Generic: Sodium Chloride, Sodium Gluconate, Sodium Acetate, Potassium Chloride, Magnesium Chloride

Verified·Apr 23, 2026
Manufacturer
Baxter
NDC
0338-9593
RxCUI
801109
Route
INTRAVENOUS
ICD-10 indication
E86.0

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About Plasma-Lyte 148 (pH 7.4)

What is this medication? Plasma-Lyte 148 (pH 7.4) is a sterile, nonpyrogenic isotonic solution designed for intravenous administration. It contains a specific blend of electrolytes, including sodium, potassium, magnesium, chloride, acetate, and gluconate, formulated to closely resemble the chemical composition of human blood plasma. Because the pH is adjusted to approximately 7.4, it is considered a balanced crystalloid solution that helps maintain normal physiological acid-base levels when administered to patients.

This medication is primarily used to replace lost fluids and electrolytes in patients who are dehydrated or undergoing surgery. It is frequently utilized for short-term volume depletion or as a source of water and electrolytes when a patient is unable to take them orally. Additionally, healthcare providers use it to treat certain types of metabolic acidosis because the acetate and gluconate components are metabolized into bicarbonate, which helps neutralize excess acid in the body.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Medicare Part D coverage

How Plasma-Lyte 148 (pH 7.4) appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

74%

4,057 of 5,509 plans

Most common tier

Tier 4

On 41% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)36
21%
Tier 2 (generic)46
27%
Tier 3 (preferred brand)18
11%
Tier 4 (non-preferred brand)69
41%
Tier 61
1%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 170 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.