How much does RIMSO-50 cost?

Pricing for RIMSO-50 varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does RIMSO-50 need prior authorization?

RIMSO-50 appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for RIMSO-50?

We haven't verified an active copay card or PAP for RIMSO-50 in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is RIMSO-50 used to treat?

RIMSO-50 (generic: Dimethyl Sulfoxide) is indicated for Cystitis, Bacterial Infections, Interstitial Cystitis. Click any condition name on this page for more detail.

Does RIMSO-50 have a generic version?

The generic name for RIMSO-50 is Dimethyl Sulfoxide. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

RIMSO-50

Generic: Dimethyl Sulfoxide

Verified·Apr 23, 2026

Manufacturer: Mylan
NDC: 67457-177
RxCUI: 208361
Route: INTRAVESICAL
ICD-10 indication: N30.10

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About RIMSO-50

What is this medication? RIMSO-50 is a prescription medication containing the active ingredient dimethyl sulfoxide, which is commonly known as DMSO. It is specifically indicated for the symptomatic relief of patients suffering from interstitial cystitis, a chronic inflammatory condition of the bladder wall. Unlike many other medications, this liquid solution is administered directly into the bladder using a catheter through a procedure called intravesical instillation.

The medication works by passing into the tissues of the bladder to help reduce inflammation and provide relief from pelvic pain and urinary frequency. It may also act as a muscle relaxant and can help increase the functional capacity of the bladder for individuals dealing with the persistent discomfort of interstitial cystitis. Treatment is typically performed in a clinical environment by a healthcare professional, and the schedule for these instillations is tailored to the specific needs and response of the patient.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Dimethyl Sulfoxide.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup RIMSO-50 →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Dimethyl Sulfoxide →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for RIMSO-50. Official source: DailyMed (NLM) · Label effective Mar 17, 2021

Indications and usage

INDICATIONS AND USAGE RIMSO-50 ® (dimethyl sulfoxide) is indicated for the symptomatic relief of patients with interstitial cystitis. RIMSO-50 ® has not been approved as being safe and effective for any other indication. There is no clinical evidence of effectiveness of dimethyl sulfoxide in the treatment of bacterial infections of the urinary tract.

Dosage and administration

DOSAGE AND ADMINISTRATION Instillation of 50 mL of RIMSO-50 ® (dimethyl sulfoxide) directly into the bladder may be accomplished by catheter or asepto syringe and allow to remain for 15 minutes. Application of an analgesic lubricant gel such as lidocaine jelly to the urethra is suggested prior to insertion of the catheter to avoid spasm. The medication is expelled by spontaneous voiding. It is recommended that the treatment be repeated every two weeks until maximum symptomatic relief is obtained. Thereafter, time intervals between therapy may be increased appropriately. Administration of oral analgesic medication or suppositories containing belladonna and opium prior to the instillation of RIMSO-50 ® can reduce bladder spasm. In patients with severe interstitial cystitis with very sensitive bladders, the initial treatment, and possibly the second and third (depending on patient response) should be done under anesthesia. (Saddle block has been suggested).

Contraindications

CONTRAINDICATIONS None known.

Warnings

WARNINGS Dimethyl sulfoxide can initiate the liberation of histamine and there has been occasional hypersensitivity reaction with topical administration of dimethyl sulfoxide. This hypersensitivity has been reported in one patients receiving intravesical RIMSO-50 ® . The physician should be cognizant of this possibility in prescribing RIMSO-50 ® . If anaphylactoid symptoms develop, appropriate therapy should be instituted.

Adverse reactions

ADVERSE REACTIONS A garlic-like taste may be noted by the patient within a few minutes after instillation of RIMSO-50 ® (dimethyl sulfoxide). This taste may last several hours and because of the presence of metabolites, an odor on the breath and skin may remain for 72 hours. Transient chemical cystitis has been noted following instillation of dimethyl sulfoxide. The patient may experience moderately severe discomfort on administration. Usually this becomes less prominent with repeated administration.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

RIMSO-50 treats a rare condition. For in-depth disease pages on our sister site:

UniteRare · Interstitial Cystitis

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.