How much does TOBRAMYCIN cost?

Pricing for TOBRAMYCIN varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does TOBRAMYCIN need prior authorization?

TOBRAMYCIN appears on 3 payer formularies in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for TOBRAMYCIN?

We haven't verified an active copay card or PAP for TOBRAMYCIN in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is TOBRAMYCIN used to treat?

TOBRAMYCIN (generic: Tobramycin) is indicated for Pseudomonas Pneumonia, Pneumonia, Sepsis. Click any condition name on this page for more detail.

TOBRAMYCIN

Generic: Tobramycin

Verified·Apr 23, 2026

Manufacturer: Eli Lilly
NDC: 63187-902
RxCUI: 597823
Route: INTRAMUSCULAR
ICD-10 indication: J15.1

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About TOBRAMYCIN

What is this medication? Tobramycin is a prescription aminoglycoside antibiotic used to eliminate bacteria that cause various types of infections. It works by binding to specific parts of the bacteria to prevent them from synthesizing essential proteins, which leads to the death of the bacterial cells. The medication is versatile and can be administered as an eye drop or ointment for ocular infections, as an inhaled solution for respiratory issues, or through an injection for more severe systemic conditions.

A significant use for the inhaled version of this medication is the treatment of chronic lung infections in patients with cystic fibrosis, specifically targeting the bacteria known as Pseudomonas aeruginosa. The ophthalmic versions are commonly used to treat bacterial conjunctivitis and other surface-level eye infections. Like all antibiotics, tobramycin is only effective against bacteria and will not provide relief for viral infections such as the common cold or influenza.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Tobramycin.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup TOBRAMYCIN →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Tobramycin →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for TOBRAMYCIN. Official source: DailyMed (NLM) · Label effective Nov 1, 2019

Indications and usage

INDICATIONS AND USAGE: Tobramycin Ophthalmic Solution USP, 0.3% is a topical antibiotic indicated in the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany the use of Tobramycin Ophthalmic Solution USP, 0.3%. Clinical studies have shown tobramycin to be safe and effective for use in pediatric patients.

Dosage and administration

DOSAGE AND ADMINISTRATION: In mild to moderate disease, instill one or two drops into the affected eye(s) every four hours. In severe infections, instill two drops into the eye(s) hourly until improvement, following which treatment should be reduced prior to discontinuation.

Contraindications

CONTRAINDICATIONS: Tobramycin Ophthalmic Solution USP, 0.3% is contraindicated in patients with known hypersensitivity to any of its components.

Warnings

WARNINGS: FOR TOPICAL OPHTHALMIC USE ONLY. NOT FOR INJECTION INTO THE EYE. Sensitivity to topically applied aminoglycosides may occur in some patients. If a sensitivity reaction to Tobramycin Ophthalmic Solution USP, 0.3% occurs, discontinue use.

Adverse reactions

ADVERSE REACTIONS: The most frequent adverse reactions to tobramycin ophthalmic solution are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than three of 100 patients treated with tobramycin. Similar reactions may occur with the topical use of other aminoglycoside antibiotics. Other adverse reactions have not been reported from tobramycin therapy; however, if topical ocular tobramycin is administered concomitantly with systemic aminoglycoside antibiotics, care should be taken to monitor the total serum concentration.

Use in pregnancy

Pregnancy Category B: Reproduction studies in three types of animals at doses up to thirty-three times the normal human systemic dose have revealed no evidence of impaired fertility or harm to the fetus due to tobramycin. There are, however, no adequate and wellcontrolled studies in pregnant women. Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How TOBRAMYCIN appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

60%

3,317 of 5,509 plans

Most common tier

Tier 4

On 42% of covering formularies

Prior authorization required

10%

of covering formularies

Tier	Formularies on this tier	Share
Tier 1 (preferred generic)	69	21%
Tier 2 (generic)	82	25%
Tier 3 (preferred brand)	40	12%
Tier 4 (non-preferred brand)	137	42%
Tier 6	1	0%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 329 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

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Medicare Part D

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Medicare Part D

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Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.