How much does TOBREX cost?

Pricing for TOBREX varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does TOBREX need prior authorization?

TOBREX appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for TOBREX?

Yes — the manufacturer copay card link is available on this page. A patient assistance program is also available for qualifying patients. Eligibility typically depends on insurance type and income. Click the CTA buttons above to apply directly through the manufacturer's portal.

What is TOBREX used to treat?

TOBREX (generic: tobramycin) is indicated for Peritonitis, Pink Eye, Bacterial Infections. Click any condition name on this page for more detail.

Does TOBREX have a generic version?

The generic name for TOBREX is tobramycin. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

TOBREX

Generic: tobramycin

Verified·Apr 23, 2026

NDC: 0078-0813
RxCUI: 207850
Route: OPHTHALMIC
ICD-10 indication: H10.31

Affordability Check

How much will you actually pay for TOBREX?

In 30 seconds, see every legitimate way to afford TOBREX — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

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About TOBREX

What is this medication? Tobrex is a prescription antibiotic medication used to treat external bacterial infections of the eye and the surrounding structures. It contains the active ingredient tobramycin, which belongs to a class of drugs known as aminoglycoside antibiotics. This medication works by stopping the growth of bacteria that cause infections such as conjunctivitis or inflammation of the eyelids. It is specifically designed for topical application directly to the eye surface and is not effective against viral or fungal eye infections.

Doctors typically prescribe Tobrex in the form of ophthalmic drops or ointment. Patients are usually instructed to apply the medication several times a day depending on the severity of the infection and the specific formulation used. Common side effects may include temporary eye redness, itching, or swelling of the eyelid. It is important to complete the full course of treatment as directed by a healthcare provider to ensure the infection is completely cleared and to prevent the development of antibiotic resistance.

Copay & patient assistance

Patient Copay Amount: First fill free for TRYPTYR (via BlinkRx trial); as little as $30 for EYSUVIS (via BlinkRx); $79 for Rocklatan, Rhopressa, and Simbrinza (Medicare Part D Direct Access Support Coupon); $60 for Inveltys (Medicare Part D Direct Access Support Coupon)
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Standard copay program requires private/commercial insurance; BlinkRx support is available for both Commercial and Medicare patients; Alcon Cares (no-cost program) requires US residency, limited or no insurance coverage, and specific household income requirements
RxBIN, PCN, and Group numbers: Not Publicly Available

Copay card →Patient Assistance Program →

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for tobramycin.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup TOBREX →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for tobramycin →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for TOBREX. Official source: DailyMed (NLM) · Label effective Dec 16, 2025

Indications and usage

INDICATIONS AND USAGE TOBREX ® (tobramycin ophthalmic ointment) 0.3 % is a topical antibiotic indicated in the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany the use of TOBREX (tobramycin ophthalmic ointment) 0.3%. Clinical studies have shown tobramycin to be safe and effective for use in children.

Dosage and administration

DOSAGE AND ADMINISTRATION In mild to moderate disease, apply a half-inch ribbon into the affected eye(s) 2 or 3 times per day. In severe infections, instill a half-inch ribbon into the affected eye(s) every 3 to 4 hours until improvement, following which treatment should be reduced prior to discontinuation. How to Apply TOBREX (tobramycin ophthalmic ointment) 0.3%: 1. Tilt your head back. 2. Place a finger on your cheek just under your eye and gently pull down until a ''V'' pocket is formed between your eyeball and your lower lid. 3. Place a small amount (about ½ inch) of TOBREX ® (tobramycin ophthalmic ointment) 0.3% in the ''V'' pocket. Do not let the tip of the tube touch your eye. 4. Look downward before closing your eye.

Contraindications

CONTRAINDICATIONS TOBREX (tobramycin ophthalmic ointment) 0.3 % is contraindicated in patients with known hypersensitivity to any of its components.

Warnings

WARNINGS NOT FOR INJECTION INTO THE EYE. Sensitivity to topically applied aminoglycosides may occur in some patients. Severity of hypersensitivity reactions may vary from local effects to generalized reactions such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions. If a sensitivity reaction to TOBREX (tobramycin ophthalmic ointment) 0.3% occurs, discontinue use.

Adverse reactions

ADVERSE REACTIONS: The most frequent adverse reactions to TOBREX (tobramycin ophthalmic ointment) 0.3% are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than three of 100 patients treated with TOBREX ® (tobramycin ophthalmic ointment) 0.3%. Postmarketing Experience: Additional adverse reactions identified from postmarketing use include anaphylactic reaction, Stevens-Johnson syndrome, and erythema multiforme. The following additional adverse reactions have been reported with systemic aminoglycosides: Neurotoxicity, ototoxicity and nephrotoxicity have occurred in patients receiving systemic aminoglycoside therapy. Aminoglycosides may aggravate muscle weakness in patients with known or suspected neuromuscular disorders, such as myasthenia gravis or Parkinson’s disease, because of their potential effect on neuromuscular function.

Use in pregnancy

Pregnancy: Reproduction studies in three types of animals at doses up to thirty-three times the normal human systemic dose have revealed no evidence of impaired fertility or harm to the fetus due to tobramycin. There are, however, no adequate and well-controlled studies in pregnant women. Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How TOBREX appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

10%

566 of 5,509 plans

Most common tier

Tier 4

On 62% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 2 (generic)	2	8%
Tier 3 (preferred brand)	8	31%
Tier 4 (non-preferred brand)	16	62%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 26 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.