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Verzenio

Generic: abemaciclib

Data may be stale·Apr 23, 2026
Manufacturer
Eli Lilly
NDC
0002-6216
RxCUI
1946830
Route
ORAL
ICD-10 indication
C50.919

Affordability Check

How much will you actually pay for Verzenio?

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About Verzenio

What is this medication?

Verzenio, known generically as abemaciclib, is a prescription medication categorized as a kinase inhibitor. It works by blocking specific proteins called cyclin-dependent kinases 4 and 6, which are involved in the growth and division of cancer cells. By inhibiting these proteins, the drug helps slow or stop the progression of hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) breast cancer.

This medication is typically prescribed for adults with advanced or metastatic breast cancer, either as a stand-alone therapy or in combination with endocrine treatments like aromatase inhibitors or fulvestrant. It is also used in certain patients with early-stage breast cancer who have a high risk of the disease returning after surgery. Healthcare providers determine the appropriate dosage and treatment plan based on the specific stage of the cancer and the patient's overall health status.

Copay & patient assistance

  • Patient Copay Amount: As little as $0 per 28-day supply.
  • Maximum Annual Benefit Limit: Up to $10,600 per calendar year (limited to 14 fills per year); if the patient is enrolled in a "Maximizer" plan, the limit is reduced to $350 per calendar year.
  • Core Eligibility Restrictions: Must have commercial insurance coverage for Verzenio; 18 years of age or older; resident of the United States or Puerto Rico; not enrolled in any state or federal government-funded healthcare program (including Medicare, Medicaid, or TRICARE); prohibited for patients using an Alternative Funding Program (AFP); requires a valid HIPAA authorization.
  • RxBIN, PCN, and Group numbers: Not Publicly Available.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Verzenio appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

28%

1,551 of 5,499 plans

Most common tier

Tier 5

On 80% of covering formularies

Prior authorization required

99%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)43
17%
Tier 2 (generic)2
1%
Tier 4 (non-preferred brand)7
3%
Tier 5 (specialty)204
80%

Step therapy: 0% of formularies

Quantity limits: 85% of formularies

Coverage breadth: 256 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.