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VITRASE

Generic: hyaluronidase, ovine

Verified·Apr 23, 2026
Manufacturer
Bausch and Lomb
NDC
24208-002
RxCUI
486166
Route
SUBCUTANEOUS
ICD-10 indication
E86.0

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About VITRASE

What is this medication? Vitrase is a prescription medication containing hyaluronidase, which is a purified enzyme derived from sheep protein. It is primarily used as an adjuvant to increase the absorption and dispersion of other injected drugs or fluids into the body's tissues. By temporarily breaking down hyaluronic acid, a natural substance that holds cells together, the medication lowers the viscosity of the connective tissue to allow injected liquids to spread more rapidly and be absorbed more effectively.

In clinical settings, Vitrase is also frequently used for hypodermoclysis, a method of providing fluids subcutaneously to patients who are dehydrated or cannot receive intravenous fluids. Additionally, it may be utilized during certain imaging procedures, such as subcutaneous urography, to help the body better absorb radiopaque agents. The effect of the medication is temporary, and the treated tissues typically return to their normal state within twenty-four to forty-eight hours after the procedure is completed.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.