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ZYNYZ

Generic: retifanlimab-dlwr

Verified·Oct 26, 2026
NDC
50881-006
RxCUI
2632985
Route
INTRAVENOUS
ICD-10 indication
C18.9

Affordability Check

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About ZYNYZ

What is this medication?

Zynyz is a prescription medication used to treat a specific type of skin cancer known as Merkel cell carcinoma in adults. It is indicated for patients with metastatic disease, meaning the cancer has spread to other parts of the body, or recurrent locally advanced disease that cannot be treated with surgery or radiation. This drug is a type of immunotherapy called a programmed death receptor-1 blocking antibody, which helps the body's own immune system find and kill cancer cells.

The medicine is administered through an intravenous infusion by a healthcare professional, usually on a schedule of every four weeks. By preventing the PD-1 protein from working, Zynyz stops cancer cells from hiding from the immune system, allowing the body to mount a more effective defense against the tumor. Because it stimulates the immune system, it may cause side effects where the body attacks its own healthy tissues, and patients should be closely supervised by their oncology team during the course of treatment.

Copay & patient assistance

  • Patient Copay Amount: $0–$15
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Patients must have commercial health insurance for the Savings Program; patients who are uninsured or underinsured may be eligible for the Patient Assistance Program to receive medication free of charge.
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

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Medicare Part D

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Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

ZYNYZ treats a rare condition. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.