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Acthar

Generic: Repository Corticotropin

Data may be stale·Apr 23, 2026
Manufacturer
Mallinckrodt
NDC
63004-8710
RxCUI
309541
Route
INTRAMUSCULAR
ICD-10 indication
G40.409

Affordability Check

How much will you actually pay for Acthar?

In 30 seconds, see every legitimate way to afford Acthar — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

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About Acthar

What is this medication? Acthar, also known as Acthar Gel, is a prescription medication that consists of repository corticotropin injection. It is an injectable hormone that works by stimulating the adrenal glands to produce natural corticosteroids, which help the body manage inflammation and immune system activity. One of its primary indications is for the treatment of infantile spasms in children under the age of two, where it serves as a specialized therapy to control certain types of seizures.

Beyond its use in infants, Acthar is also utilized to treat a wide range of inflammatory and autoimmune conditions in adults. It is frequently prescribed to manage acute exacerbations of multiple sclerosis and to treat symptoms associated with systemic lupus erythematosus, rheumatoid arthritis, and psoriatic arthritis. Additionally, it can be used for the treatment of nephrotic syndrome and respiratory conditions like sarcoidosis. By mimicking the action of natural hormones, the drug helps to suppress overactive immune responses and reduce swelling throughout the body.

Copay & patient assistance

  • Patient Copay Amount: $0 (Provided at no cost to eligible patients)
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Must have a valid, on-label prescription for an FDA-approved indication; must be a permanent US resident; household income must be at or below 700% of the Federal Poverty Level; must be uninsured, underinsured, or rendered uninsured; program is currently not available for patients using the Acthar Gel Single-Dose Pre-filled SelfJect Injector.
  • RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Acthar appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).

Covered by plans

3%

180 of 5,499 plans

Most common tier

Tier 5

On 85% of covering formularies

Prior authorization required

100%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)1
8%
Tier 2 (generic)1
8%
Tier 5 (specialty)11
85%

Step therapy: 0% of formularies

Quantity limits: 38% of formularies

Coverage breadth: 13 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

—

Medicare Part D

Yes——

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

Acthar treats 2 rare conditions. For in-depth disease pages on our sister site:

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.