Acthar
Generic: Repository Corticotropin
- Manufacturer
- Mallinckrodt
- NDC
- 63004-8710
- RxCUI
- 309541
- Route
- INTRAMUSCULAR
- ICD-10 indication
- G40.409
Affordability Check
How much will you actually pay for Acthar?
In 30 seconds, see every legitimate way to afford Acthar — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Acthar
What is this medication? Acthar, also known as Acthar Gel, is a prescription medication that consists of repository corticotropin injection. It is an injectable hormone that works by stimulating the adrenal glands to produce natural corticosteroids, which help the body manage inflammation and immune system activity. One of its primary indications is for the treatment of infantile spasms in children under the age of two, where it serves as a specialized therapy to control certain types of seizures.
Beyond its use in infants, Acthar is also utilized to treat a wide range of inflammatory and autoimmune conditions in adults. It is frequently prescribed to manage acute exacerbations of multiple sclerosis and to treat symptoms associated with systemic lupus erythematosus, rheumatoid arthritis, and psoriatic arthritis. Additionally, it can be used for the treatment of nephrotic syndrome and respiratory conditions like sarcoidosis. By mimicking the action of natural hormones, the drug helps to suppress overactive immune responses and reduce swelling throughout the body.
Copay & patient assistance
- Patient Copay Amount: $0 (Provided at no cost to eligible patients)
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Must have a valid, on-label prescription for an FDA-approved indication; must be a permanent US resident; household income must be at or below 700% of the Federal Poverty Level; must be uninsured, underinsured, or rendered uninsured; program is currently not available for patients using the Acthar Gel Single-Dose Pre-filled SelfJect Injector.
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Repository Corticotropin.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Acthar →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for Repository Corticotropin →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Acthar appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-08-31).
Covered by plans
3%
180 of 5,499 plans
Most common tier
Tier 5
On 85% of covering formularies
Prior authorization required
100%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 1 | 8% |
| Tier 2 (generic) | 1 | 8% |
| Tier 5 (specialty) | 11 | 85% |
Step therapy: 0% of formularies
Quantity limits: 38% of formularies
Coverage breadth: 13 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | Yes | — | — |
Related drugs
Purified Cortrophin Gel
Same generic · Repository Corticotropin
Oxygen/Nitrogen 40/60
Treats same condition · Oxygen/Nitrogen 40/60
INDOMETHACIN
Treats same condition · Indomethacin
BACLOFEN
Treats same condition · Baclofen
Diflunisal
Treats same condition · Diflunisal
Diclofenac DR
Treats same condition · Diclofenac
Physician EZ Use Joint Tunnel and Trigger Kit
Treats same condition · AMMONIA, LIDOCAINE HYDROCHLORIDE, TRIAMCINOLONE ACETONIDE, POVIDONE-IODINE
Prednisolone Sodium Phosphate Oral Solution
Treats same condition · prednisoLONE sodium phosphate
Avonex, Avonex Pen, AVONEX
Treats same condition
JYLAMVO
Treats same condition · Methotrexate
How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.
Rare-disease navigation (specialists, trials, patient communities)
Acthar treats 2 rare conditions. For in-depth disease pages on our sister site:
UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.