Esomeprazole Magnesium
Generic: esomeprazole magnesium
- NDC
- 37808-364
- RxCUI
- 606726
- Route
- ORAL
- ICD-10 indication
- K21.9
Affordability Check
How much will you actually pay for Esomeprazole Magnesium?
In 30 seconds, see every legitimate way to afford Esomeprazole Magnesium — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.
About Esomeprazole Magnesium
What is this medication?
Esomeprazole magnesium is a prescription medication belonging to a group of drugs known as proton pump inhibitors. It functions by decreasing the amount of acid produced by the stomach, which helps manage various digestive conditions. It is most commonly prescribed for the treatment of gastroesophageal reflux disease, often referred to as GERD. By lowering stomach acidity, the medication helps alleviate uncomfortable symptoms such as chronic heartburn and acid regurgitation while allowing the esophagus time to recover from acid-related irritation.
In addition to managing reflux, esomeprazole magnesium is frequently used to treat and prevent gastric ulcers caused by long-term use of certain pain relievers like nonsteroidal anti-inflammatory drugs. It is also an essential part of treatment plans for healing erosive esophagitis and for eradicating Helicobacter pylori infections when used in combination with specific antibiotics. Furthermore, it may be utilized to control rare medical conditions that cause the stomach to produce extreme amounts of acid, such as Zollinger-Ellison syndrome.
Copay & patient assistance
- Patient Copay Amount: Not Publicly Available
- Maximum Annual Benefit Limit: Not Publicly Available
- Core Eligibility Restrictions: Not Publicly Available
- RxBIN, PCN, and Group numbers: Not Publicly Available
External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.
Compare pricing elsewhere
RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.
Cost Plus Drug Company
Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for esomeprazole magnesium.
Browse Cost Plus medications →
GoodRx
Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.
Lookup Esomeprazole Magnesium →
NeedyMeds
Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.
Search for esomeprazole magnesium →
RxAssist
PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.
Search PAPs →
We deep-link because transparency helps patients. None of these partners pay RxCopays.
Prescribing information
From the FDA-approved label for Esomeprazole Magnesium. Official source: DailyMed (NLM) · Label effective Oct 28, 2025
Indications and usage
Dosage and administration
Warnings
Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.
Conditions we've indexed resources for
Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.
Medicare Part D coverage
How Esomeprazole Magnesium appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).
Covered by plans
74%
4,102 of 5,509 plans
Most common tier
Tier 2
On 39% of covering formularies
Prior authorization required
0%
of covering formularies
| Tier | Formularies on this tier | Share |
|---|---|---|
| Tier 1 (preferred generic) | 79 | 26% |
| Tier 2 (generic) | 121 | 39% |
| Tier 3 (preferred brand) | 90 | 29% |
| Tier 4 (non-preferred brand) | 19 | 6% |
Step therapy: 17% of formularies
Quantity limits: 81% of formularies
Coverage breadth: 309 of 65 formularies
How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).
Prior authorization & coverage
| Payer | PA | Step therapy | Copay tier |
|---|---|---|---|
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
— Medicare Part D | — | — | — |
Related drugs
Esomeprazole Magnesium DR
Same generic · Esomeprazole Magnesium
Esomeprazole Magnesium for delayed-release oral suspension
Same generic · Esomeprazole Magnesium
NEXIUM
Same generic · Esomeprazole magnesium
esomeprazole
Same generic · esomeprazole magnesium
PANTOPRAZOLE SODIUM I.V.
Treats same condition · PANTOPRAZOLE SODIUM
Esomeprazole DR
Treats same condition · Esomeprazole DR
Protonix I.V.
Treats same condition · pantoprazole sodium
Ranitidine Hydrochloride
Treats same condition · Ranitidine Hydrochloride
Omeprazole/Bicarbonate
Treats same condition · Omeprazole and Sodium Bicarbonate
Dexlansoprazole
Treats same condition · Dexlansoprazole
How this page is sourced
- Drug identity verified against openFDA NDC Directory.
- Label text (when shown) originates from NLM DailyMed.
- Copay and assistance URLs verified periodically; if you hit a broken link, tell us.