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FLUOCINONIDE

Generic: FLUOCINONIDE

Verified·Apr 23, 2026
Manufacturer
Syntex
NDC
51672-1273
RxCUI
310364
Route
TOPICAL
ICD-10 indication
L30.9

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About FLUOCINONIDE

What is this medication?

Fluocinonide is a high-potency topical corticosteroid used to treat a wide range of inflammatory skin conditions. It is primarily prescribed to manage symptoms of disorders such as eczema, psoriasis, seborrheic dermatitis, and various allergic reactions that manifest on the skin. By reducing the activity of chemicals in the body that cause inflammation, the medication helps to relieve redness, swelling, and intense itching. It is available in several topical formulations, including creams, ointments, gels, and solutions, which allows healthcare providers to choose the best medium for the specific area being treated.

This medication works by suppressing the localized immune response that leads to skin irritation and discomfort. Because fluocinonide is categorized as a high-strength steroid, it is generally intended for short-term use or for treating particularly stubborn skin patches rather than for long-term maintenance. Patients are usually advised to apply it sparingly and avoid covering the treated area with airtight bandages unless instructed otherwise, as this can increase the risk of side effects. Following a doctor's guidance is essential to ensure the medication effectively clears skin issues while minimizing risks such as skin thinning or systemic absorption.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Prescribing information

From the FDA-approved label for FLUOCINONIDE. Official source: DailyMed (NLM) · Label effective Jul 1, 2025

Indications and usage
INDICATIONS AND USAGE Fluocinonide Topical Solution USP, 0.05% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION Fluocinonide Topical Solution USP, 0.05% is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Hypertrichosis Maceration of the skin Itching Acneiform eruptions Secondary infection Irritation Hypopigmentation Skin atrophy Dryness Perioral dermatitis Striae Folliculitis Allergic contact dermatitis Miliaria
Use in pregnancy
Pregnancy Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How FLUOCINONIDE appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

76%

4,186 of 5,509 plans

Most common tier

Tier 2

On 32% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)80
25%
Tier 2 (generic)102
32%
Tier 3 (preferred brand)85
27%
Tier 4 (non-preferred brand)53
17%

Step therapy: 0% of formularies

Quantity limits: 71% of formularies

Coverage breadth: 320 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.