Skip to main content

Fluocinonide Cream

Generic: FLUOCINONIDE

Verified·Apr 23, 2026
NDC
69238-1534
RxCUI
310364
Route
TOPICAL
ICD-10 indication
L40.9

Affordability Check

How much will you actually pay for Fluocinonide Cream?

In 30 seconds, see every legitimate way to afford Fluocinonide Cream — Medicare copay, manufacturer copay card, Patient Assistance Program, grants, or cash.

Check my options →

About Fluocinonide Cream

What is this medication? Fluocinonide cream is a high-potency topical corticosteroid used to treat a variety of inflammatory skin conditions. It is primarily prescribed to alleviate symptoms such as redness, itching, swelling, and discomfort associated with conditions like psoriasis, atopic dermatitis, and allergic reactions. By reducing the immune system response in the localized area where it is applied, the medication helps clear up rashes and soothe irritated skin. This medication works by inhibiting the release of inflammatory chemicals in the body, which effectively calms the affected skin cells. Because it is a potent steroid, it is typically intended for short-term use and should be applied thinly to the affected areas as directed by a healthcare provider. Patients are generally advised to avoid using it on the face, groin, or underarms unless specifically instructed, and it should not be used on broken or infected skin.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Fluocinonide Cream. Official source: DailyMed (NLM) · Label effective Jun 6, 2023

Indications and usage
INDICATIONS AND USAGE Fluocinonide Cream USP, 0.05% is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION Fluocinonide Cream USP, 0.05% is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.
Adverse reactions
ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Folliculitis Hypertrichosis Acneiform Eruptions Hypopigmentation Perioral Dermatitis Allergic Contact Dermatitis Maceration of the Skin Secondary Infection Skin Atrophy Striae Miliaria To report SUSPECTED ADVERSE REACTIONS, contact Amneal Pharmaceuticals at 1-877-835-5472 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch .
Use in pregnancy
Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Fluocinonide Cream appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

76%

4,186 of 5,509 plans

Most common tier

Tier 2

On 32% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)80
25%
Tier 2 (generic)102
32%
Tier 3 (preferred brand)85
27%
Tier 4 (non-preferred brand)53
17%

Step therapy: 0% of formularies

Quantity limits: 71% of formularies

Coverage breadth: 320 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.