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Sodium Sulfacetamide

Generic: Sodium Sulfacetamide

Verified·Apr 23, 2026
NDC
52187-530
RxCUI
1006107
Route
TOPICAL
ICD-10 indication
L21.0

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About Sodium Sulfacetamide

What is this medication? Sodium sulfacetamide is a prescription antibiotic medication that belongs to the group of drugs known as sulfonamides. It is primarily used to treat various types of bacterial infections by stopping the growth of certain bacteria. This medication is available in different forms depending on the area being treated, including eye drops or ointments for the eyes and lotions, cleansers, or creams for the skin.

When applied to the eyes, it is commonly prescribed to treat conditions such as bacterial conjunctivitis and other superficial eye infections. In its topical form for the skin, it is frequently used to manage conditions like acne vulgaris, seborrheic dermatitis, and rosacea. It works by interfering with the ability of bacteria to produce folic acid, which is essential for their survival and multiplication.

Copay & patient assistance

  • Patient Copay Amount: Not Publicly Available
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not Publicly Available
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Sodium Sulfacetamide. Official source: DailyMed (NLM) · Label effective Dec 22, 2020

Indications and usage
INDICATIONS: This product is indicated for use in the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis.
Dosage and administration
DOSAGE AND ADMINISTRATION: Apply this product once or twice daily to affected areas, or as directed by your physician. Wet skin and liberally apply to areas to be cleansed. Massage gently into skin for 10-20 seconds, working into a full lather, rinse thoroughly and pat dry. If drying occurs, it may be controlled by rinsing off sooner or using less often.
Contraindications
CONTRAINDICATIONS: This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product. This product is not to be used by patients with kidney disease.
Warnings
WARNINGS: Sulfonamides are known to cause Stevens-Johnson syndrome in hypersensitive individuals. Stevens-Johnson syndrome also has been reported following the use of sodium sulfacetamide topically. Cases of drug-induced systemic lupus erythematosus from topical sulfacetamide also have been reported. In one of these cases, there was a fatal outcome. KEEP OUT OF THE REACH OF CHILDREN.
Adverse reactions
ADVERSE REACTIONS: Reports of irritation and hypersensitivity to sodium sulfacetamide are uncommon. The following adverse reactions, reported after administration of sterile ophthalmic sodium sulfacetamide, are noteworthy: instances of Stevens-Johnson syndrome and instances of local hypersensitivity which progressed to a syndrome resembling systemic lupus erythematosus; in one case a fatal outcome was reported (see WARNINGS).

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.