How much does Synalar cost?

Pricing for Synalar varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Synalar need prior authorization?

Synalar appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Synalar?

We haven't verified an active copay card or PAP for Synalar in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Synalar used to treat?

Synalar (generic: fluocinolone acetonide) is indicated for Eczema. Click any condition name on this page for more detail.

Does Synalar have a generic version?

The generic name for Synalar is fluocinolone acetonide. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Synalar

Generic: fluocinolone acetonide

Verified·Apr 23, 2026

Manufacturer: Medimetriks
NDC: 43538-900
RxCUI: 1191315
Route: TOPICAL
ICD-10 indication: L30.9

Affordability Check

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About Synalar

What is this medication?

Synalar is a prescription topical corticosteroid that contains the active ingredient fluocinolone acetonide. It is primarily used to treat a wide variety of skin conditions characterized by inflammation, redness, and persistent itching. The medication works by suppressing the immune response in the local area where it is applied, which helps to reduce the swelling and discomfort associated with irritated skin. It is manufactured in different forms, including creams, ointments, and topical solutions, to ensure it can be applied effectively to different parts of the body and various types of skin lesions.

Doctors typically prescribe Synalar for the management of conditions such as eczema, psoriasis, seborrheic dermatitis, and allergic contact dermatitis. Because it is classified as a medium-potency steroid, it is effective for moderate symptoms but must be used strictly according to a healthcare provider's instructions. Patients are generally advised to apply a thin film to the affected area and avoid using occlusive dressings, like bandages or plastic wrap, unless specifically told to do so. To minimize the risk of side effects such as skin thinning or systemic absorption, the medication is usually intended for short-term use rather than long-term daily application.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for fluocinolone acetonide.

Browse Cost Plus medications →

GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Synalar →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for fluocinolone acetonide →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Synalar. Official source: DailyMed (NLM) · Label effective Jul 18, 2024

Indications and usage

INDICATIONS AND USAGE SYNALAR ® Cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteriod-responsive dermatoses.

Dosage and administration

DOSAGE AND ADMINISTRATION SYNALAR ® Cream is generally applied to the affected area as a thin film from two to four times daily depending on the severity of the condition. In hairy sites, the hair should be parted to allow direct contact with the lesion. Occlusive dressing may be used for the management of psoriasis or recalcitrant conditions. Some plastic films may be flammable and due care should be exercised in their use. Similarly, caution should be employed when such films are used on children or left in their proximity, to avoid the possibility of accidental suffocation. If an infection develops, the use of the occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.

Contraindications

CONTRAINDICATIONS Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Adverse reactions

ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Hypertrichosis Maceration of the skin Itching Acneiform eruptions Secondary infection Irritation Hypopigmentation Skin atrophy Dryness Perioral dermatitis Striae Folliculitis Allergic contact dermatitis Miliaria

Use in pregnancy

Pregnancy Category C Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Eczema

Medicare Part D coverage

How Synalar appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

41 of 5,509 plans

Most common tier

Tier 4

On 100% of covering formularies

Prior authorization required

of covering formularies

Tier	Formularies on this tier	Share
Tier 4 (non-preferred brand)	5	100%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 5 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

—

Medicare Part D

—

Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.