Urea 39% Cream

What is this medication? Urea 39% Cream is a high-strength topical medication categorized as a keratolytic agent. It is primarily used to treat skin conditions that result in dry, rough, or thickened skin, such as psoriasis, eczema, corns, and calluses. The cream works by softening the keratin in the skin, which helps to dissolve the intercellular matrix and promotes the shedding of dead skin cells. By increasing the skin's ability to hold onto water, it effectively hydrates and smooths areas that have become excessively hardened or scaly. Beyond its use for skin texture, this specific concentration of urea is often prescribed for the treatment of damaged or thickened nails. When applied to a diseased nail plate, the medication softens the nail, making it easier for a healthcare provider to remove or for the patient to gradually debride the area. This process is particularly helpful for managing fungal infections or ingrown nails without the need for invasive surgical procedures. It is important to use this medication exactly as prescribed and to avoid contact with the eyes or sensitive mucous membranes.