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Mydriacyl

Generic: tropicamide

Verified·Apr 23, 2026
Manufacturer
Alcon
NDC
0065-0355
RxCUI
208660
Route
OPHTHALMIC
ICD-10 indication
Z01.00

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About Mydriacyl

What is this medication?

Mydriacyl is an ophthalmic solution primarily used to enlarge the pupil of the eye during a medical examination. It contains the active ingredient tropicamide, which belongs to a class of drugs known as anticholinergics. By blocking certain nerve impulses to the muscles of the iris, the medication allows eye care professionals to get a clear and detailed view of the internal structures of the eye, such as the retina and the optic nerve.

In addition to pupil dilation, this medication is used to temporarily relax the focusing muscles within the eye. This process, known as cycloplegia, is helpful for determining an accurate lens prescription, particularly in children or patients who may have difficulty controlling their eye focus. The effects typically begin within a few minutes of application and can last for several hours, during which time a patient may experience increased sensitivity to light and temporary blurred vision.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for Mydriacyl. Official source: DailyMed (NLM) · Label effective Dec 22, 2022

Indications and usage
INDICATIONS AND USAGE For mydriasis and cycloplegia for diagnostic procedures.
Dosage and administration
DOSAGE AND ADMINISTRATION For refraction, instill one or two drops of 1% solution in the eye(s), repeated in five minutes. If patient is not seen within 20 to 30 minutes, an additional drop may be instilled to prolong mydriatic effect. For examination of fundus, instill one or two drops of 0.5% solution 15 or 20 minutes prior to examination. Individuals with heavily pigmented irides may require higher strength or more doses. Mydriasis will reverse spontaneously with time, typically in 4 to 8 hours. However, in some cases, complete recovery may take up to 24 hours.
Contraindications
CONTRAINDICATIONS Contraindicated in persons showing hypersensitivity to any component of this preparation.
Warnings
WARNINGS FOR TOPICAL OPHTHALMIC USE ONLY. NOT FOR INJECTION. This preparation may cause CNS disturbances which may be dangerous in pediatric patients. The possibility of psychotic reactions and behavioral disturbances due to hypersensitivity to anticholinergic drugs should be considered. Mydriatics may produce a transient elevation of intraocular pressure. Remove contact lenses before using.
Drug interactions
Drug Interactions Tropicamide may interfere with the antihypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.
Adverse reactions
ADVERSE REACTIONS Ocular: Transient stinging, blurred vision, photophobia and superficial punctate keratitis have been reported with the use of tropicamide. Increased intraocular pressure has been reported following the use of mydriatics. Non-Ocular: Dryness of the mouth, tachycardia, headache, allergic reactions, nausea, vomiting, pallor, central nervous system disturbances and muscle rigidity have been reported with the use of tropicamide. Psychotic reactions, behavioral disturbances, and vasomotor or cardiorespiratory collapse in children have been reported with the use of anticholinergic drugs.
Use in pregnancy
Pregnancy Animal reproduction studies have not been conducted with tropicamide. It is also not known whether tropicamide can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Tropicamide should be given to a pregnant woman only if clearly needed.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

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Prior authorization & coverage

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.