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Pramosone

Generic: hydrocortisone acetate and pramoxine hydrochloride

Verified·Apr 23, 2026
Manufacturer
Sebela
NDC
83107-014
RxCUI
1234512
Route
TOPICAL
ICD-10 indication
L30.9

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About Pramosone

What is this medication? Pramosone is a prescription topical medication that combines two active ingredients to treat various skin conditions. It contains hydrocortisone, which is a corticosteroid, and pramoxine, which serves as a local anesthetic. This combination is effective for managing inflammatory skin disorders such as eczema, allergic reactions, and dermatitis. It works by reducing the swelling, redness, and overall immune response in the affected area.

The medication is primarily used to provide relief from intense itching and pain associated with skin irritation. While the hydrocortisone component addresses the underlying inflammation, the pramoxine helps to numb the skin surface to offer relief from physical discomfort. It is available in several forms, including creams, lotions, and ointments, and is often prescribed for conditions where both inflammation and severe itching are present simultaneously.

Copay & patient assistance

  • Patient Copay Amount: As little as $10 out-of-pocket costs for many eligible patients
  • Maximum Annual Benefit Limit: Not Publicly Available (Note: Website specifies "Unlimited refills" but does not list a maximum annual dollar cap)
  • Core Eligibility Restrictions: Not valid for prescriptions reimbursed in whole or in part under Medicaid, Medicare (including Medicare Advantage and Part D), or any other federal or state program; offer good only in the USA at participating retail pharmacies; cannot be redeemed at government-subsidized clinics; not valid where prohibited, taxed, or restricted; may not be combined with any other rebate, coupon, free trial, or similar offer
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Pramosone. Official source: DailyMed (NLM) · Label effective Mar 18, 2026

Indications and usage
INDICATIONS AND USAGE: Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION: Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Occlusive dressing may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressing should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS: Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS: The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Foliculitis Hypertrichosis Acneiform eruptions Hypopigmentation Perioral dermatitis Allergic contact dermatitis Maceration of the skin Secondary infection Skin atrophy Striae Miliaria
Use in pregnancy
Pregnancy: Teratogenic Effects: Pregnancy Category C: Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Pramosone appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

0%

21 of 5,509 plans

Most common tier

Tier 4

On 100% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 4 (non-preferred brand)3
100%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 3 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.