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Analpram HC

Generic: hydrocortisone acetate and pramoxine hydrochloride

Verified·Apr 23, 2026
Manufacturer
Sebela
NDC
83107-018
RxCUI
1235049
Route
TOPICAL
ICD-10 indication
L30.9

Affordability Check

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About Analpram HC

What is this medication?

Analpram HC is a prescription topical medication used primarily to treat inflammation, itching, and discomfort in the anal and rectal areas. It contains a combination of two active ingredients: hydrocortisone and pramoxine. Hydrocortisone belongs to a class of drugs known as corticosteroids, which work by reducing swelling, redness, and itching. Pramoxine is a local anesthetic that helps to numb the skin and provide temporary relief from pain and irritation.

Doctors typically prescribe this medication for patients suffering from conditions such as hemorrhoids, anal fissures, or proctitis. By combining an anti-inflammatory agent with a numbing agent, the cream or lotion provides dual-action relief for localized symptoms. It is usually applied directly to the affected area several times a day as directed by a healthcare provider to manage flare-ups and improve patient comfort.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

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Prescribing information

From the FDA-approved label for Analpram HC. Official source: DailyMed (NLM) · Label effective Jun 24, 2025

Indications and usage
INDICATIONS AND USAGE: Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION: Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS: Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS: The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Itching Irritation Dryness Foliculitis Hypertrichosis Acneiform eruptions Hypopigmentation Perioral dermatitis Allergic contact dermatitis Maceration of the skin Secondary infection Skin atrophy Striae Miliaria
Use in pregnancy
Pregnancy: Teratogenic Effects: Pregnancy Category C: Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Medicare Part D coverage

How Analpram HC appears across Medicare Part D plan formularies nationally. Source: CMS monthly Prescription Drug Plan file (2026-04-30).

Covered by plans

5%

259 of 5,509 plans

Most common tier

Tier 2

On 38% of covering formularies

Prior authorization required

0%

of covering formularies

TierFormularies on this tierShare
Tier 1 (preferred generic)1
8%
Tier 2 (generic)5
38%
Tier 3 (preferred brand)4
31%
Tier 4 (non-preferred brand)3
23%

Step therapy: 0% of formularies

Quantity limits: 0% of formularies

Coverage breadth: 13 of 65 formularies

How to read this:plans on the same formulary share tier + PA rules. Your specific plan's copay depends on (a) the tier above, (b) your plan's cost-share for that tier, (c) whether you're in the initial coverage phase or past the 2026 $2,000 out-of-pocket cap. For your exact plan, check its Summary of Benefits or log in to your Medicare.gov account. Copay cards don't apply to Medicare (federal law).

Prior authorization & coverage

PayerPAStep therapyCopay tier

Medicare Part D

Related drugs

How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.