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Pramosone Cream

Generic: hydrocortisone acetate and pramoxine hydrochloride

Verified·Apr 23, 2026
Manufacturer
Sebela
NDC
83107-016
RxCUI
1234512
Route
TOPICAL
ICD-10 indication
L30.9

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About Pramosone Cream

What is this medication? Pramosone cream is a prescription topical medication that contains a combination of two active ingredients: hydrocortisone and pramoxine. Hydrocortisone belongs to a class of drugs known as corticosteroids, which work by reducing inflammation, redness, and swelling in the skin. Pramoxine is a local anesthetic that helps to numb the skin surface, providing relief from pain and intense itching. Together, these components work to address both the underlying irritation and the uncomfortable physical sensations associated with various skin ailments.

This medication is primarily used to treat inflammatory skin conditions such as eczema, various types of dermatitis, and allergic rashes. It is particularly effective for managing skin issues that are accompanied by significant itching or discomfort. Patients typically apply a thin layer of the cream to the affected area as directed by their healthcare provider. Because it contains a steroid, it is generally intended for specific durations of use and should be applied exactly as prescribed to minimize the risk of potential side effects like skin thinning.

Copay & patient assistance

  • Patient Copay Amount: As little as $10
  • Maximum Annual Benefit Limit: Not Publicly Available
  • Core Eligibility Restrictions: Not valid for prescriptions reimbursed under Medicaid, Medicare (including Medicare Advantage and Part D), or any other federal or state program; offer good only in the USA at participating retail pharmacies; cannot be redeemed at government-subsidized clinics; may not be combined with any other rebate, coupon, free trial, or similar offer
  • RxBIN, PCN, and Group numbers: Not Publicly Available

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Prescribing information

From the FDA-approved label for Pramosone Cream. Official source: DailyMed (NLM) · Label effective Jun 30, 2025

Indications and usage
INDICATIONS AND USAGE: Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dosage and administration
DOSAGE AND ADMINISTRATION: Topical corticosteroids are generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy instituted.
Contraindications
CONTRAINDICATIONS: Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Adverse reactions
ADVERSE REACTIONS : The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning Hypertrichosis Maceration of the skin Itching Acneiform eruptions Secondary infection Irritation Hypopigmentation Skin atrophy Dryness Perioral dermatitis Striae Folliculitis Allergic contact dermatitis Miliaria
Use in pregnancy
Pregnancy: Teratogenic Effects: Pregnancy Category C: Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.