How much does Urea 40 Percent cost?

Pricing for Urea 40 Percent varies by insurance plan, dose, and pharmacy. Our database does not show a fixed cost because prices change faster than we can verify. For current pharmacy prices, check your insurance's formulary tier (in the prior-authorization section), use the GoodRx or Cost Plus Drugs deep links on this page, or ask your pharmacist to run a test claim. If a copay card is listed, it usually drops the out-of-pocket significantly for commercial insurance.

Does Urea 40 Percent need prior authorization?

Urea 40 Percent appears on 1 payer formulary in our database. PA requirements vary by payer — see the prior-authorization table on this page for specifics. In general, specialty and brand-name drugs are more likely to require PA than generic equivalents.

Is there a copay card or patient assistance program for Urea 40 Percent?

We haven't verified an active copay card or PAP for Urea 40 Percent in our current data. Check NeedyMeds or RxAssist for independent directories, or submit what you find via our "Report a broken link" form.

What is Urea 40 Percent used to treat?

Urea 40 Percent (generic: Urea) is indicated for Dermatitis, Psoriasis, Eczema and 1 other condition. Click any condition name on this page for more detail.

Does Urea 40 Percent have a generic version?

The generic name for Urea 40 Percent is Urea. Whether a generic is currently available depends on patent status — check the FDA Orange Book or ask your pharmacist. Generics are often substantially cheaper than brand-name drugs.

Urea 40 Percent

Generic: Urea

Verified·Apr 23, 2026

NDC: 72162-1668
RxCUI: 198342
Route: TOPICAL
ICD-10 indication: L85.0

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About Urea 40 Percent

What is this medication? Urea 40 percent is a high-potency topical medication classified as a keratolytic agent, which means it helps break down and soften thickened or hardened skin. It is primarily prescribed to treat hyperkeratotic conditions such as psoriasis, eczema, ichthyosis, and severe calluses or corns. By increasing the moisture content of the skin and dissolving the protein matrix that holds dead skin cells together, this medication promotes the shedding of rough skin and restores a smoother texture to affected areas. In addition to treating skin conditions, urea 40 percent is frequently used for the non-surgical debridement of damaged or diseased nails. When applied to the nails, it helps soften and thin the nail plate, making it easier to remove sections affected by fungal infections or physical trauma. This process allows for better penetration of subsequent antifungal treatments and can help relieve pressure associated with thickened or ingrown nails. The medication is for external use only and should be applied exactly as directed by a healthcare professional.

Copay & patient assistance

Patient Copay Amount: Not Publicly Available
Maximum Annual Benefit Limit: Not Publicly Available
Core Eligibility Restrictions: Not Publicly Available
RxBIN, PCN, and Group numbers: Not Publicly Available

External links go directly to the manufacturer's portal. RxCopays does not receive compensation for referrals.

Compare pricing elsewhere

RxCopays doesn't sell drugs or take referral fees. Here are the transparent-pricing directories we recommend checking alongside your insurance formulary.

Cost Plus Drug Company

Mark Cuban's transparent-pricing pharmacy — manufacturer cost + 15% markup + $5 dispensing fee. No insurance needed. Search alphabetically for Urea.

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GoodRx

Compare local pharmacy prices with GoodRx coupons. Use the price with your insurance or without — whichever is cheaper.

Lookup Urea 40 Percent →

NeedyMeds

Independent nonprofit directory of patient assistance programs, copay cards, and charity co-pay foundations.

Search for Urea →

RxAssist

PAP directory maintained by Volunteers in Health Care at Brown University. Free, no ads.

Search PAPs →

We deep-link because transparency helps patients. None of these partners pay RxCopays.

Prescribing information

From the FDA-approved label for Urea 40 Percent. Official source: DailyMed (NLM) · Label effective Mar 27, 2026

Indications and usage

INDICATIONS: This product is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, xerosis, ichthyosis, skin cracks and fissures, dermatitis, eczema, psoriasis, keratoses and calluses.

Dosage and administration

DOSAGE AND ADMINISTRATION: Use as directed by your physician. See label booklet for full Prescribing Information.

Contraindications

CONTRAINDICATIONS: This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.

Warnings

WARNINGS: FOR EXTERNAL USE ONLY. NOT FOR OPHTHALMIC USE. KEEP OUT OF REACH OF CHILDREN. Avoid contact with eyes, lips and mucous membranes. General: This product is to be used as directed by a physician and should not be used to treat any condition other than that for which it was prescribed. If redness or irritation occurs, discontinue use and consult a physician. Information for Patients: Patients should discontinue the use of this product if the condition becomes worse or if a rash develops in the area being treated or elsewhere. Avoid contact with eyes, lips and mucous membranes. Carcinogenesis, Mutagenesis and Impairment of Fertility: Long-term animal studies for carcinogenic potential have not been performed on this product to date. Studies on reproduction and fertility also have not been performed. Pregnancy: Category C . Animal reproduction studies have not been conducted with this product. It is also not known whether this product can affect reproduction capacity or cause fetal harm when administered to a pregnant woman. This product should be used by a pregnant woman only if clearly needed or when potential benefits outweigh potential hazards to the fetus. Nursing Mothers: It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this product is administered to a nursing woman.

Adverse reactions

ADVERSE REACTIONS: Transient stinging, burning, itching or irritation may occur and normally disappear upon discontinuing the use of this product.

Use in pregnancy

Pregnancy: Category C . Animal reproduction studies have not been conducted with this product. It is also not known whether this product can affect reproduction capacity or cause fetal harm when administered to a pregnant woman. This product should be used by a pregnant woman only if clearly needed or when potential benefits outweigh potential hazards to the fetus.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

Payer	PA	Step therapy	Copay tier
— Medicare Part D	—	—	—

Payer

Step therapy

Copay tier

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Medicare Part D

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Related drugs

How this page is sourced

Drug identity verified against openFDA NDC Directory.
Label text (when shown) originates from NLM DailyMed.
Copay and assistance URLs verified periodically; if you hit a broken link, tell us.

Rare-disease navigation (specialists, trials, patient communities)

Urea 40 Percent treats a rare condition. For in-depth disease pages on our sister site:

UniteRare · Acquired Ichthyosis

UniteRare.org is our sister site for rare-disease navigation — same editorial team, same accuracy standards.