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UREDEX

Generic: UREA

Verified·Apr 23, 2026
Manufacturer
Terra-Medica
NDC
85622-601
RxCUI
198886
Route
TOPICAL
ICD-10 indication
L85.9

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About UREDEX

What is this medication? Uredex is a prescription topical medication primarily used to treat dry, rough, or scaly skin conditions. It belongs to a class of drugs known as keratolytics, which work by softening and dissolving the hard protein called keratin that holds dead skin cells together in the outer layer of the skin. By increasing moisture levels and promoting the shedding of dead tissue, it helps to alleviate the discomfort and appearance associated with conditions like eczema, psoriasis, and various forms of dermatitis. This medication is also frequently prescribed to manage hyperkeratotic conditions, which involve an abnormal thickening of the skin. It helps to break down thickened areas and can even be used to help soften damaged or ingrown nails to make them easier to treat or remove. Because it draws water into the skin layers, it provides deep hydration and improves the overall texture of the affected area, making the skin feel significantly smoother and more supple over time.

Copay & patient assistance

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program for more details.

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Prescribing information

From the FDA-approved label for UREDEX. Official source: DailyMed (NLM) · Label effective Jan 16, 2026

Indications and usage
INDICATIONS: For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis palmaris, keratoderma, corns and calluses, as well as damaged, ingrown and devitalized nails.
Dosage and administration
DOSAGE AND ADMINISTRATION: Apply to affected area(s) twice per day or as directed by a physician. Rub in until completely absorbed. Apply to diseased or damaged nail(s) twice per day, or as directed by a physician.
Contraindications
CONTRAINDICATIONS: This product is contraindicated in persons with known or suspected hypersensitivity to any of the ingredients of the product.
Warnings
WARNING: KEEP OUT OF REACH OF CHILDREN.
Adverse reactions
ADVERSE REACTIONS: Transient stinging, burning, itching or irritation may occur and normally disappear upon discontinuing the use of this product.

Label text is reproduced as-is from the FDA-approved label. We do not paraphrase, summarize, or omit. Content above is for informational purposes only and is not medical advice. Always consult your prescribing clinician or pharmacist before making decisions about your medication.

Conditions we've indexed resources for

Click a condition to see copay cards, grants, and PA rules specific to it. For the full list of FDA-approved indications, see Prescribing information above.

Prior authorization & coverage

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Medicare Part D

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How this page is sourced

  • Drug identity verified against openFDA NDC Directory.
  • Label text (when shown) originates from NLM DailyMed.
  • Copay and assistance URLs verified periodically; if you hit a broken link, tell us.